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2024

Volume 5, Issue 2, p42-78

Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.

Cerebrovascular Dysfunction in Alzheimer’s Disease and Transgenic Rodent Models

Alzheimer’s Disease (AD) and Alzheimer’s Disease-Related Dementia (ADRD) are the primary causes of dementia that has a devastating effect on the quality of life and is a tremendous economic burden on the healthcare system. The accumulation of extracellular beta-amyloid (Aβ) plaques and intracellular hyperphosphorylated tau-containing neurofibrillary tangles (NFTs) in the brain are the hallmarks of AD.

J Exp Neurol, 2024, Volume 5, Issue 2, p42-64 | DOI: 10.33696/Neurol.5.087

Treatment of Sleep Disorders in Children with Atopic Dermatitis: What's New?

Atopic dermatitis (AD), also known as atopic eczema, is a chronic and inflammatory disease caused by an interaction of genetic, immunological, and environmental factors. It is characterized by skin lesions and itching and progresses with periods of improvement and worsening.

J Exp Neurol, 2024, Volume 5, Issue 2, p65-72 | DOI: 10.33696/Neurol.5.088

Homeostatic Synaptic Plasticity may be Targeted for the Prevention of Post-Stroke Epilepsy

Stroke is the most common cause of acquired epilepsy, with up to 30 percent of stroke survivors developing epilepsy over time. However, the mechanisms leading to neuronal hyperexcitability and epilepsy in stroke survivors are not fully understood. In a recently published work, we demonstrate that ischemic stroke induces homeostatic plasticity regulation in the surviving neurons in the peri-stroke area.

J Exp Neurol, 2024, Volume 5, Issue 2, p73-78 | DOI: 10.33696/Neurol.5.089

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