Archives of Medical Case Reports

It is long known that melanoma has the ability to metastasize widely. Unusual sites of metastases are seen including intracardiac. The literature reports cases of cardiac metastases however, most reports pre-date the more recent era of immunotherapy and targeted agent use and do not describe systemic treatment responses.

Since December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused by 2019 Novel Coronavirus (2019-nCoV) has resulted in 89,000 cases of Corona Virus Disease 2019 (COVID-19), formerly known as Novel Coronavirus Pneumonia (NCP) in China, including 2,450 deaths.

Meningiomas are common, primary brain tumors, accounting for up to 30% of intracranial neoplasms; they are usually slow-growing and benign [1]. Primary extra cranial meningiomas are rare, and approximately 2% of meningiomas are located extra cranially [2]. Furthermore, primary extra cranial meningiomas of the ear and temporal bone are exceedingly rare .

The double trigger (DT) is the second asynchrony in frequency, after the failed cycles [1]. Compared to the latter, it can be more injurious since it usually increases tidal volume (Vt), transmural and transvascular pressure to levels that can cause ventilator-induced lung damage [2,3]; and self-inflicted by the patient (P_SILI) [4], as well diaphragmatic injury.

The genus Babesia comprises over 100 species of tick-transmitted protozoal intraerythrocytic pathogens (piroplasms) [1], causing malarial-type illness. The most common human pathogens in the United States are B. microti [2] and Babesia duncani (WA- 1) [3]; Less common species include Babesia MO-1 [4] and KO-1 [5], as well as Babesia divergens and Babesia venatorum (EU-1) in Europe.

Primary tumors of the small bowel are a rare condition, accounting for 2 to 3% of gastrointestinal tumors. Malignant melanoma is the most common metastatic tumor found in the gastrointestinal tract [1]. It can be localized in different sites, from the oral cavity to the anus. It can also be present as a primary lesion.

Osmotic Demyelination Syndrome (ODS) is a unique process of selective demyelination and destruction of oligodendrocytes and astrocytes in specific areas of the brain that usually occurs a few days after an osmotic stress [1]. ODS has been described most frequently in association with a rapid correction of hyponatremia, though it may occur with other electrolyte or metabolic abnormalities.

Red cell membrane in patients with haemoglobin H (Hb-H) disease and other haemoglobinopathies is rigid and thus red blood cells are fragmented during passage through narrow capillary beds, especially through the splenic sinusoids and the liver [1,2]. These fragments are frequently seen in peripheral blood films.

Meningiomas are common, primary brain tumors, accounting for up to 30% of intracranial neoplasms; they are usually slow-growing and benign [1]. Primary extra cranial meningiomas are rare, and approximately 2% of meningiomas are located extra cranially [2]. Furthermore, primary extra cranial meningiomas of the ear and temporal bone are exceedingly rare .

5-fluorouracil (5-FU), an antimetabolite in the fluoropyrimidine class, is the third most commonly used chemotherapeutic agent worldwide for the treatment of solid malignancies [1]. Despite advances in novel cancer therapies, commonly used in combination with fluoropyrimidines, 5-FU remains one of the most effective and safe chemotherapy agents to manage colorectal cancer (CRC).

Arbovirology, Arbovirus, Arthropod-borne virus, these are informal name that refers to all virus types infecting “blood sucker” arthropod vector, capable to multiply the virus and to transmit it to vertebrates through their bite. These virus-vectors are essentially mosquitoes (male only), ticks and sandflies feeding mainly on mammals and sometime on other vertebrates (e.g. birds, reptiles).

The incidence of chronic diseases is rapidly increasing worldwide. It has been calculated that, in 2001, chronic diseases contributed to approximately 46% of the global burden of disease and 60% of the total reported deaths with that number expected to increase to 57% by 2020, when chronic diseases will account for almost 75% of all deaths worldwide.

Imatinib is a selective inhibitor of the bcr-abl tyrosine kinase making it a potential treatment of chronic myelogenous leukemia (CML), as well as a selective inhibitor of KIT protein tyrosine kinase, and PDGF receptor, and is the treatment of choice in patients with gastrointestinal stromal tumors (GISTs)

Since December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused by 2019 Novel Coronavirus (2019-nCoV) has resulted in 89,000 cases of Corona Virus Disease 2019 (COVID-19), formerly known as Novel Coronavirus Pneumonia (NCP) in China, including 2,450 deaths.

A 59-year-old left hand dominant female was evaluated by a physical therapist. The patient had an 8-year history of chronic intermittent left elbow pain with a recent exacerbation occurring after moving furniture. Aggravating factors included holding a coffee cup, picking up trash bags, and lifting heavy dishes. Symptoms were eased by ice and Meloxicam as prescribed by her primary care provider.

The double trigger (DT) is the second asynchrony in frequency, after the failed cycles [1]. Compared to the latter, it can be more injurious since it usually increases tidal volume (Vt), transmural and transvascular pressure to levels that can cause ventilator-induced lung damage [2,3]; and self-inflicted by the patient (P_SILI) [4], as well diaphragmatic injury.

5-fluorouracil (5-FU), an antimetabolite in the fluoropyrimidine class, is the third most commonly used chemotherapeutic agent worldwide for the treatment of solid malignancies [1]. Despite advances in novel cancer therapies, commonly used in combination with fluoropyrimidines, 5-FU remains one of the most effective and safe chemotherapy agents to manage colorectal cancer (CRC).

Wound healing is a dynamic process whereby cellular structures and the tissue layers are reconstructed. Adult wound healing can be categorized into three stages: inflammatory phase, proliferative phase, and remodelling phase. Blood cells like macrophages, neutrophils, extracellular matrix and mediators, various proteins, and various genes play an important role in these phases.