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Journal of Clinical Haematology
ISSN: 2766-4686
Volume 5, Issue 1, p1-3
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Treatment of Traumatic Brain Injury: Nanotherapeutics
Nanotechnology and regenerative nanotherapeutics enrich the renewing features and function of the diseased cells and tissue by replenishing the local environment, while inhibiting further degeneration. These featured therapeutics perform cell maintenance and promote cellular events to develop better communication between re-forming molecules of remedies and the brain.
J Clin Haematol, 2024, Volume 5, Issue 1, p1-3 | DOI: 10.33696/haematology.5.056DNA Nanotechnology Engineered Vesicle for Mimicking Biomolecular Signaling
Bio-inspired strategy is kind of interesting to fabricate devices and perform dynamic operations [1]. Various devices have been made, such as airplane, radar and submarine. In life science, as the fundamental entity, million years’ evolution enables cell becomes the most successful functionality.
Development of Metal Oxide Nanoparticles as Semiconductors
The variety of methods employed during the fabrication of MONPs can alter the characteristics and control the properties of the obtained nano-oxides. The reaction mechanisms and, therefore, the functionality of nanostructured MOx depend on their composition
Exploiting Nanotechnology to Target Viruses
Infectious diseases caused by microorganisms of the most varied natures and by viral entities cause millions of deaths every year. Around the world, viral infections have impacted civilizations’ circumstances since the earliest times, including the current panorama of the SARS-CoV-2 pandemic known as coronavirus disease in 2019 (COVID-19). In this sense, in the last century,
Multidirectional Benefits of Nanotechnology in the Diagnosis, Treatment and Prevention of Tuberculosis
Despite the curious advancement in medical science and therapeutics, tuberculosis (TB) persist the primary factor of mortality than any other infectious disease and socioeconomic disaster for millions of people around the world. According to the World Health Organization (WHO), World’s One-third of the population is infected with this disease and of these, 8 to 10 million people develop active disease and 2 million people die each year and the rest of the infected people remain asymptomatic.
Dendorbium Nobile Lindl. Alkaloids Suppress NF-κB and NLRP3 Signaling Pathways to Attenuate Lipopolysaccharide-induced Neuroinflammation
The important immune cells in the brain are called microglia acting as the central junction between neuroinflammation and neurodegenerative diseases. In patients of cognitive disorders and Alzheimer’s disease (AD) animal models, amoebic morphology and inflammatory pathways are activated to release numerous cells in the inflammatory factors by active microglia.
Green Nanotechnology: The Influence of Intermolecular and Supramolecular Interactions
In the last decade, the study of nanometer-scale particles has grown exponentially worldwide. This growth is due to the broad field of nanostructures applications, which, due to their dimensions in nanometric sizes, have new properties not found in micro and macro scale. These properties result from the increase in the ratio between the surface area and volume, and the nanostructures’ size directly influences these. Tolerance to temperature, variety of colors, changes in chemical reactivity,
Nanotechnology in Water Treatment: An Optimistic Perspective for the Near Future
Unequal access to drinking water and basic sanitation are old issues in Brazil and worldwide. Besides, this situation foments the proliferation of infectious parasitic diseases. Moreover, mainly in underdeveloped countries, it victimizes socioeconomically vulnerable people. The degree of water contamination analysis, usually by fecal matter, is made by the number of microorganisms present in the sample, including Escherichia coli or thermotolerant coliforms. In addition, several
Nanotechnology for Water Purification – Current Trends and Challenges
Environmental pollution is a significant concern in both developing and developed countries. The pollution load in the environment accumulates as a result of anthropogenic activity. Both organic and inorganic contaminants are hazardous to living things, and their incidence and persistence have risen dramatically in current years.
A Review on Nanotechnology: Applications in Food Industry, Future Opportunities, Challenges and Potential Risks
Nanotechnology is an evolving revolution with enormous promise in a variety of fields, including mechanics, medicine, and the food business. Nanoparticles owing to having greater surface area and enhanced rates of mass transfer seem to pose higher biological and chemical activities, penetrability, catalytic behaviour, enzymatic reactivity, and quantum
Emerging Potential of Plant Virus Nanoparticles (PVNPs) in Anticancer Immunotherapies
Plant virus nanoparticles (PVNPs) are increasingly recognized and studied for use in biomedical applications. PVNPs include plant virions with self-assembled capsid protein coats (PC) that encapsulate the virus genome, and virus-like particles (VLPs), a capsid without the viral genome.
LncZFAS1 Inhibit MPP+-Induced Neuroinflammation Through TXNIP/MIB1 E3 Ubiquitin Ligase/NLRP3 Axis
Recently researchers have focused on the role of neuroinflammation in neurodegenerative diseases such as Alzheimer’s disease, atrophic lateral sclerosis, Huntington’s disease, Multiple sclerosis and Parkinson’s disease (PD). PD is one of the leading neurodegenerative diseases in developed countries and the complete etiological scenario remains unknown. A-synuclein misfolding and aggregation, mitochondrial dysfunction, dysfunctional protein clearance and ubiquitin/proteasome systems, and neuroinflammation have been associated with PD.
Photocatalytic Degradation of Organic Dyes Using Titanium Dioxide (TiO2) and Mg-TiO2 Nanoparticles
Titanium dioxide (TiO2 ) based nano-sized photocatalysts (NPCs) were synthesized following a green method from the extract of Peepal (Ficus religiosa) leaves and titanium tetrachloride as precursors. Doping of TiO2 with Magnesium (Mg) was done using magnesium chloride through the method of chemical precipitation. Size of the NPC samples were estimated and characterized by CPS Disc Centrifuge, Diffracted Light Scattering (DLS) and Field Emission Gun Scanning Electron Microscopy (FEG-SEM) techniques.
A Short Commentary of Nanotechnology on Traditional Chinese Medicine
Nanotechnology is the art of science manipulating matter at the nanoscale about 1 to 100 nanometers, 10-9 nm ranging from a sheet of paper (100,000 nanometers thick) to a human hair (around 80,000-100,000 nanometers).
Biological and Non-Conventional Synthesis of Zinc Oxide Nanoparticles (ZnO-NPs): Their Potential Applications
In nature, nanoparticles can be found as natural or synthetic. Nanoparticles may form either physically or chemically. Nanoparticles are uniform types of common material whose dimensions are less than 100 nm. Volcanic ash, ocean spray, fine sand, and dust are some examples of natural nanoparticles.
Neuroinflammation and Microglial Polarity: Sirolimus Shifts Microglial Polarity to M2 phenotype in a Mouse Model of Tuberous Sclerosis Complex
Tuberous sclerosis complex (TSC) is a neurocutaneous syndrome characterized by systemic hamartomas, including skin and neural symptoms. Many patients exhibit epilepsy, intellectual disability, autism, and other behavioral and neuropsychiatric symptoms, referred to as TSCassociated neuropsychiatric disorders (TAND).
The Regulation Impact of Naringenin-loaded Chitosan Nanoparticles on Succinate Dehydrogenase Activity in Cancer Cells
Oxidative phosphorylation dysregulation (OXPHOS) has been demonstrated to be essential for the development of cancer. Therefore, it may be argued that chaperone and deacetylase activities modulate OXPHOS activity. For instance, a complicated network of interactions connects a cell’s bioenergetic features and neoplastic potential through the imbalance of sirtuin 3 (SIRT3) and succinate dehydrogenase (SDH) enzymatic activity in mitochondria.
Treatment of Traumatic Brain Injury: Nanotherapeutics
Nanotechnology and regenerative nanotherapeutics enrich the renewing features and function of the diseased cells and tissue by replenishing the local environment, while inhibiting further degeneration. These featured therapeutics perform cell maintenance and promote cellular events to develop better communication between re-forming molecules of remedies and the brain.
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