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Journal of Diabetes and Clinical Research
ISSN: 2689-2839
Lawrence Lavery
The University of Texas Southwestern Medical Center, USA
Sex Differences in Diabetic Ocular Surface Complications and Dysregulation of the OGF-OGFr Pathway
Prevalence of Cardiovascular Risk Factors in Osteoarthritis Patients Derived from Primary Care Records: A Systematic Review of Observational Studies
Dysregulation of the OGF-OGFr Pathway and Associated Diabetic Complications
Journal of Diabetes and Clinical Research is an international publication initiated with the motto of stimulating the research in diabetes disease management and treatment. The journal focuses on various aspects of diabetes and clinical research such as diabetes and trials, neuropathology of diabetes, diabetes and innovative therapies, merging technologies in disease management etc.
Elevated Opioid Growth Factor Alters the Limbus in Type 1 Diabetic Rats
Ocular surface complications occur in more than 50% of individuals diagnosed with diabetes. The financial and health-related burden of diabetes is increasing annually. Several major ocular complications associated with diabetes involve the limbus. The vascular limbus, adjacent to the avascular cornea, is the source of circulating growth factors, elevated glucose, and cytokines for the cornea.
A Commentary on “Better TIR, HbA1c, and Less Hypoglycemia in Closed-loop Insulin System in Patients with Type 1 Diabetes: A Meta-analysis”
Our team’s previous meta-analysis aimed to evaluate the efficacy and safety of closed-loop insulin system (CLS) in non-pregnant individuals with type 1 diabetes mellitus (T1DM). In this study, we aim to discuss the broader application of CLS in a more diverse population and address the current challenges and future development directions.
Plasma Non-Esterified Fatty Acids (NEFA) in Type 2 Diabetes Mellitus: Evidence on Pathophysiology
Type 2 diabetes mellitus (T2DM) is a metabolic dysfunction characterized by elevated levels of blood glucose as well as impaired lipid and protein metabolism. The mobilization of fatty acids is augmented in insulin resistance due to the failure of lipolysis inhibition by the hormone that further augments the increase in plasma NEFA levels.
Vitamin D and Insulin Resistance in Polycystic Ovarian Syndrome and Congenital Adrenal Hyperplasia-a Commentary and Natural Expansion
In our previous focused review, the journal emphasized Type 2 diabetes (T2DM), excluding intimately associated disorders that should be considered integral components of the insulin resistance (IR) syndrome e.g., polycystic ovarian syndrome (PCOS), congenital adrenal hyperplasia (CAH), and gout.
Validation of a New Test for Assessing the Quality of Life Perceived in Patients with Type 1 Diabetes
The World Health Organization defines quality of life (QoL) as “the perception that an individual has of his life, in the context of the culture in which he lives, integrating personal goals, expectations and concerns, well-being and discomfort”.
Improved Wound Closure Rates and Mechanical Properties Resembling Native Skin in Murine Diabetic Wounds Treated with a Tropoelastin and Collagen Wound Healing Device
Chronic, non-healing, or slow to heal wounds present a significant and growing health problem in the United States, with an estimated 6.5 million people affected, at an annual cost of US $20 billion, with the highest risk groups represented by the elderly and the increasing prevalence of lifestyle diseases such as diabetes and obesity.
Risks and Prevalence of Diabetic Retinopathy in Children and Young People with Type 1 Diabetes Mellitus
Type 1 diabetes (T1D) is associated with microvascular and macrovascular complications.Duration of diabetes, poor glycaemic control, high blood pressure and proteinuria are reported risk factors contributing to the development of diabetes related complications.
Can Vitamin D Supplementation Reduce Insulin Resistance and Hence the Risks of Type 2 Diabetes?
The question of whether or not correction of vitamin D deficiency might reduce the risks of later type 2 diabetes mellitus (T2DM) has been under debate for many decades. The necessity of vitamin D for normal insulin secretion was first identified experimentally in the 1980s.
Vitamin D and Insulin Resistance in Polycystic Ovarian Syndrome and Congenital Adrenal Hyperplasia-a Commentary and Natural Expansion
In our previous focused review, the journal emphasized Type 2 diabetes (T2DM), excluding intimately associated disorders that should be considered integral components of the insulin resistance (IR) syndrome e.g., polycystic ovarian syndrome (PCOS), congenital adrenal hyperplasia (CAH), and gout.
Adapting the Escape Room to Engage Learners Two Ways During COVID-19
When creating the project, “An Escape Room Simulation Focused on Renal-Impairment for Prelicensure Nursing Students” [1] the author’s goal was to increase positive health outcomes for patients with acute kidney injury (AKI). AKI is complicated, but nurses who can help identify those at risk for the disorder and help initiate early treatment can improve patients’ results.
Improved Wound Closure Rates and Mechanical Properties Resembling Native Skin in Murine Diabetic Wounds Treated with a Tropoelastin and Collagen Wound Healing Device
Chronic, non-healing, or slow to heal wounds present a significant and growing health problem in the United States, with an estimated 6.5 million people affected, at an annual cost of US $20 billion, with the highest risk groups represented by the elderly and the increasing prevalence of lifestyle diseases such as diabetes and obesity.
Risks and Prevalence of Diabetic Retinopathy in Children and Young People with Type 1 Diabetes Mellitus
Type 1 diabetes (T1D) is associated with microvascular and macrovascular complications.Duration of diabetes, poor glycaemic control, high blood pressure and proteinuria are reported risk factors contributing to the development of diabetes related complications.
Resveratrol Treatment Reduces Neuromotor Impairment and Hearing Loss in a Mouse Model of Diabetic Neuropathy and Nerve Injury
In the peripheral nervous system (PNS), Schwann cells (SCs) are responsible for myelin production, which contributes to axonal protection and allows for efficient action potential transmission. Unfortunately, acquired and hereditary demyelinating diseases of the PNS are numerous and affect an increasing number of people.
Can Vitamin D Supplementation Reduce Insulin Resistance and Hence the Risks of Type 2 Diabetes?
The question of whether or not correction of vitamin D deficiency might reduce the risks of later type 2 diabetes mellitus (T2DM) has been under debate for many decades. The necessity of vitamin D for normal insulin secretion was first identified experimentally in the 1980s.
Validation of a New Test for Assessing the Quality of Life Perceived in Patients with Type 1 Diabetes
The World Health Organization defines quality of life (QoL) as “the perception that an individual has of his life, in the context of the culture in which he lives, integrating personal goals, expectations and concerns, well-being and discomfort”.
Adapting the Escape Room to Engage Learners Two Ways During COVID-19
When creating the project, “An Escape Room Simulation Focused on Renal-Impairment for Prelicensure Nursing Students” [1] the author’s goal was to increase positive health outcomes for patients with acute kidney injury (AKI). AKI is complicated, but nurses who can help identify those at risk for the disorder and help initiate early treatment can improve patients’ results.
Can Monoclonal Antibodies against CGRP Offer New Treatment Options for Type 2 Diabetes?
The neuropeptide Calcitonin Gene-Related Peptide (CGRP) is a 37-amino acid peptide, with a wide-range of biological activities including vasodilation, neurogenic inflammation, immune function and hypertension. In addition to these various roles, it has also been heavily implicated in metabolic disease, with roles in feeding, energy dissipation processes and pancreatic β-cell insulin secretion.
Resveratrol Treatment Reduces Neuromotor Impairment and Hearing Loss in a Mouse Model of Diabetic Neuropathy and Nerve Injury
In the peripheral nervous system (PNS), Schwann cells (SCs) are responsible for myelin production, which contributes to axonal protection and allows for efficient action potential transmission. Unfortunately, acquired and hereditary demyelinating diseases of the PNS are numerous and affect an increasing number of people.
Insulin Signal Transduction is Impaired in the Type 2 Diabetic Retina
With increasing rates of obesity, rates of type 2 diabetes and diabetic complications are expected to rise exponentially over the next few decades (American Diabetic Association). A key feature of type 2 diabetes is a resistance to insulin. Insulin signaling is key to a number of physiological processes, including glucose metabolism, cell growth, general gene expression, and apoptosis.
Cut-off Value of Random Blood Glucose among Asian Indians for Preliminary Screening of Persons with Prediabetes and Undetected Type 2 Diabetes Defined by the Glycosylated Haemoglobin Criteria
Type 2 diabetes (T2D) remains undiagnosed for many years in large number of persons living in developing countries. The cost of diagnostic tests and the invasive procedures involved in conventional screening methods remain a major setback to timely testing
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