Journal of Diabetes and Clinical Research

Commentary Open Access

Validation of a New Test for Assessing the Quality of Life Perceived in Patients with Type 1 Diabetes

Pala L, Cosentino C, Acciaioli S, Dicembrini I, Lazzeretti L, Rotella F, Mannucci E

The World Health Organization defines quality of life (QoL) as “the perception that an individual has of his life, in the context of the culture in which he lives, integrating personal goals, expectations and concerns, well-being and discomfort”.

Commentary Open Access

Adapting the Escape Room to Engage Learners Two Ways During COVID-19

Laura Wynn

When creating the project, “An Escape Room Simulation Focused on Renal-Impairment for Prelicensure Nursing Students” [1] the author’s goal was to increase positive health outcomes for patients with acute kidney injury (AKI). AKI is complicated, but nurses who can help identify those at risk for the disorder and help initiate early treatment can improve patients’ results.

Commentary Open Access

Can Monoclonal Antibodies against CGRP Offer New Treatment Options for Type 2 Diabetes?

Celine E Riera

The neuropeptide Calcitonin Gene-Related Peptide (CGRP) is a 37-amino acid peptide, with a wide-range of biological activities including vasodilation, neurogenic inflammation, immune function and hypertension. In addition to these various roles, it has also been heavily implicated in metabolic disease, with roles in feeding, energy dissipation processes and pancreatic β-cell insulin secretion.

Research Article Open Access

Resveratrol Treatment Reduces Neuromotor Impairment and Hearing Loss in a Mouse Model of Diabetic Neuropathy and Nerve Injury

Sergio Gonzalez-Gonzalez, Chantal Cazevieille, Bastien Caumes

In the peripheral nervous system (PNS), Schwann cells (SCs) are responsible for myelin production, which contributes to axonal protection and allows for efficient action potential transmission. Unfortunately, acquired and hereditary demyelinating diseases of the PNS are numerous and affect an increasing number of people.

Research Article Open Access

Insulin Signal Transduction is Impaired in the Type 2 Diabetic Retina

Youde Jiang, Li Liu, Hainan Li, Jie-Mei Wang, Jena J. Steinle

With increasing rates of obesity, rates of type 2 diabetes and diabetic complications are expected to rise exponentially over the next few decades (American Diabetic Association). A key feature of type 2 diabetes is a resistance to insulin. Insulin signaling is key to a number of physiological processes, including glucose metabolism, cell growth, general gene expression, and apoptosis.

Short Communication Open Access

Cut-off Value of Random Blood Glucose among Asian Indians for Preliminary Screening of Persons with Prediabetes and Undetected Type 2 Diabetes Defined by the Glycosylated Haemoglobin Criteria

Priscilla Susairaj, Chamukuttan Snehalatha, Arun Raghavan, Arun Nanditha, Ramachandran Vinitha, Krishnamoorthy Satheesh, Desmond G Johnston, Nicholas J Wareham, Ambady Ramachandran

Type 2 diabetes (T2D) remains undiagnosed for many years in large number of persons living in developing countries. The cost of diagnostic tests and the invasive procedures involved in conventional screening methods remain a major setback to timely testing

Commentary Open Access

Commentary: A Herbal Treatment for Type 2 Diabetes – The Dangers of Adulterated and Falsified Products

David W Holt, Atholl Johnston

In 2018, our group published a letter in The Lancet detailing a case in which a patient had taken a herbal preparation to treat her diabetes [1]. In essence, our laboratory was approached by the treating physician after the patient, a 58 year old lady of south Asian origin with a 30 year history of type 2 diabetes said that, during the previous two years, she had replaced some of her prescribed anti-diabetic medication with a herbal remedy purchased in India.

Editorial Open Access

Global Syndemic of Metabolic Diseases: Editorial Comments

Gundu H. R. Rao

Editorial is usually a brief article, written by the editor that expresses publishers or journals collective views on a current issue. As an Emeritus Professor, I have taken the liberty of writing these editorial comments, at the invitation of the Editorial Board of the Journal of Diabetes and Clinical Research.