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Journal of Diabetes and Clinical Research
ISSN: 2689-2839
Latest Articles
Long-term Effects of Continuous Subcutaneous Insulin Infusion in Adults with Type 2 Diabetes Mellitus Patients: A Six-year Follow-up Retrospective Analysis
Soo-Bong Choi
The aim of this study was to evaluate the long-term effects of continuous subcutaneous insulin infusion (CSII) therapy on the improvement of metabolic control and beta-cell function in patients with type 2 diabetes mellitus. A single-center retrospective observational study was carried out in patients with T2DM who required CSII therapy due to suboptimal glycemic control. T2DM patients treated with the DANA-R Diabe care insulin pump (SOOIL Development Co., Ltd.) was followed for 6 years.
J Diabetes Clin Res, 2026, Volume 8, Issue 1, p10-18 | DOI: 10.33696/diabetes.8.074
Clinical Inertia in the Management of Patients with Uncontrolled Type 2 Diabetes: A Retrospective Cohort Study
Jubran Boulos , Eiman Amoor , Riad Taher
This study investigated clinical inertia in the management of type 2 diabetes mellitus (T2DM), a major challenge in clinical practice. The primary aim was to assess the delay in therapeutic intensification among patients with persistently elevated hemoglobin A1c (HbA1c) levels (>8.0%) who were already receiving two oral antidiabetic drugs, considering the availability of newer effective therapies. We conducted a retrospective cohort study using data from the Clalit Health Service database in Israel.
J Diabetes Clin Res, 2026, Volume 8, Issue 1, p1-9 | DOI: 10.33696/diabetes.8.073
Treatment Challenges in a Complex Presentation of Diabetic Ketoacidosis, Hyperosmolar Hyperglycemic Syndrome and Hypernatremia: A Case Report
Parth Dhamelia, MBBS , Sara Mulville, MPAS , Peyton Lester, APRN , Preston Skinner , Nicolas Tapia Stoll , Aleksandra Murawska Baptista, MD , Abhinav Singla, MD
Overlap between diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS) is associated with significantly higher mortality than either condition alone. While hypertonic (trans locational) hyponatremia is common in hyperglycemic crises, clinically significant hypernatremia in mixed DKA/HHS presents with certain treatment challenges due to rapid osmotic shifts during insulin therapy. A 40-year-old woman with non-significant past medical history presented with vomiting, polyuria, polydipsia, and confusion for two days.
J Diabetes Clin Res, 2026, Volume 8, Issue 1, p22-27 | DOI:
Health Care Systems and Policy: Role of Leadership in the Obesity Crisis
Ayanda C. Mkhize, BS , Michael Anaafi, BS , Nehemiah Nashas , Akram Lusanda , Jessica L. Jones, MD, MSPH
Sato’s article “Decline in Physical Activity after Age 35 Increases the Risk of Obesity, Insulin Resistance, and Diabetes” highlights the obesity and diabetes crises, offering strategies to mitigate these illnesses through health promotion programs and personal motivation. To promote population behavior change, approaches that include societal, structural and personal influences are imperative.
J Diabetes Clin Res, 2026, Volume 8, Issue 1, p19-21 | DOI: