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2021

Volume 2, Issue 1, p1-61

Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.

Short Communication Open Access

Retroviral Elements in Human Evolution and Neural Development

Tongguang Wang, Tara T. Doucet-O’Hare, Lisa Henderson, Rachel P. M. Abrams, Avindra Nath

Human embryogenesis and the development of its most unique product, the human brain, are believed to be precisely regulated by factors adopted during human
evolution that differentiate us from other species.

J Exp Neurol, 2021, Volume 2, Issue 1, p1-9 | DOI: 10.33696/Neurol.2.028

Short Communication Open Access

Cathepsin D: A Candidate Link between Amyloid β-protein and Tauopathy in Alzheimer Disease

Caitlin N. Suire, Malcolm A. Leissring

Alzheimer disease (AD) is a debilitating neurodegenerative disorder characterized by extracellular deposition of the amyloid β-protein (Aβ) and intraneuronal accumulation of the microtubule-associated protein, tau

J Exp Neurol, 2021, Volume 2, Issue 1, p10-15 | DOI: 10.33696/Neurol.2.029

Short Communication Open Access

Atrial Fibrillation, Atrial Cardiopathy and Cryptogenic Strokes

Jindong Xu, Pramod Sethi, Rizwan Sabir

Cryptogenic stroke (CS) refers to the cerebral infarcts for which no definite cause is identified after adequate diagnostic evaluation. It accounts for 10-15% of all
strokes. Most of the cryptogenic strokes are embolicappearing non-lacunar infarcts based on the radiographic pattern.

J Exp Neurol, 2021, Volume 2, Issue 1, p16-20 | DOI: 10.33696/Neurol.2.030

Commentary Open Access

Commentary on Vulnerability and Resilience to Activity- Based Anorexia and the Role of Dopamine

Jeff A. Beeler, Nesha S. Burghardt

Anorexia nervosa (AN) is an eating disorder characterized by a fear of gaining weight and self-starvation, leading to life-threatening weight loss [1]. It occurs predominately in women and frequently begins during adolescence.

J Exp Neurol, 2021, Volume 2, Issue 1, p21-28 | DOI: 10.33696/Neurol.2.031

Commentary Open Access

Commentary: Use of BACTRAC Proteomic Database-Uromodulin Protein Expression During Ischemic Stroke

Gabriella-Salome K. Armstrong, Jacqueline A. Frank, Christopher J. McLouth, Ann Stowe, Jill M. Roberts, Amanda L. Trout, Justin F. Fraser, Keith Pennypacker

Uromodulin (UMOD) is a glycoprotein expressed by the epithelial cells of the thick ascending limb of Henle’s loop in the kidney. Research has shown that increased uromodulin expression may be associated with lower risk of cardiovascular disease in adults.

J Exp Neurol, 2021, Volume 2, Issue 1, p29-33 | DOI: 10.33696/Neurol.2.032

Commentary Open Access

Commentary on “Health-related Quality of Life and Posttraumatic Stress Disorder in Inpatients Injured in the Ludian Earthquake: A Longitudinal Study”

Wanqiu Yang, Lin Chen, Guangjie Zhang, Xinjin Zou, Wen Chen, Yu Liu, Yubo Huang

Posttraumatic stress disorder (PTSD) is a common psychiatric disorder after experiencing trauma exposure and characterized by at least one symptom from the four clusters: intrusion, avoidance, negative mood and cognitive alterations, as well as abnormal arousal and reactivity

J Exp Neurol, 2021, Volume 2, Issue 1, p34-38 | DOI: 10.33696/Neurol.2.033

Commentary Open Access

Stroke, Oxygen and Prehospital Care: A Commentary on Current Treatments and Opportunities for Improvement

John Collins, Igor Rybinnik, Bryan Fischberg, Jonathan McCoy

Stroke is a common and very serious illness where timely evaluation and intervention can have dramatic effects on patient outcomes.

J Exp Neurol, 2021, Volume 2, Issue 1, p39-46 | DOI: 10.33696/Neurol.2.034

Commentary Open Access

Posterior Circulation Tandem Occlusions- Classification and Techniques: A Commentary

Shelly Sharma, Michael McAree, Hekmat Zarzour

Posterior circulation tandem occlusion is an area of neurosurgery that has not been heavily studied, particularly in regards to treatment modalities. These strokes occur more rarely than other forms of stroke and, frequently, conventional surgical intervention is no longer an option by the time patients present to the hospital.

J Exp Neurol, 2021, Volume 2, Issue 1, p47-48 | DOI: 10.33696/Neurol.2.035

Research Article Open Access

Glutaminergic Signaling in the Nucleus Accumbens Modulates the Behavioral Response to Acute and Chronic Methylphenidate

Thomas Ming, Nachum Dafny

Methylphenidate (MPD) is a psychostimulant that is widely used to treat attention deficit hyperactivity disorder, and is being increasingly misused as a recreational drug and cognitive enhancer

J Exp Neurol, 2021, Volume 2, Issue 1, p49-61 | DOI: 10.33696/Neurol.2.036

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