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Journal of Clinical Cardiology
ISSN: 2694-5088
Volume 3, Issue 2, p35-70
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Prognosis of Patients with Advanced Liver Disease and Positive Stress Echocardiograms: Impact of Coronary Artery Disease, Non-alcoholic Steatohepatitis, and Beta-blocker Therapy
Cardiac Complications are the leading cause of mortality after orthotopic liver transplantation. Advanced liver disease patients with positive DSE are at increased risk. CAD, beta blocker use and NASH are independently associated with cardiac events.
J Clin Cardiol, 2022, Volume 3, Issue 2, p35-42 | DOI: 10.33696/cardiology.2.032Estimated Plasma Volume Status (ePVS) for Diastolic Heart Failure in the Intensive Care Unit: A Retrospective Cohort Study
Diastolic heart failure (DHF) is also be regarded as heart failure with preserved ejection fraction (HFpEF), is estimated to occur in 40 to 50% of patients with HF. More than 70% of HF patients over the age of 65 had HFpEF, and the incidence and prevalence of HFpEF has been increased by 10% every 10 years in comparison to HF with reduced ejection fraction (HFrEF), and this gap is expected to widen in the coming years.
J Clin Cardiol, 2022, Volume 3, Issue 2, p43-46 | DOI: 10.33696/cardiology.2.033Beta 3-Adrenergic Receptor (β3-AR) Activation at the End of Sustained Ischemia and/or Early Reperfusion may Prove to be a Valuable Cardioprotective Strategy
The contribution of β3-AR activation towards ischemiareperfusion (IR) damage largely depends on the disease stage, severity, experimental model as well as drug specificities which should be considered when investigating β3-AR pharmacology for potential therapeutic applications. These conceptions largely contribute to the discrepancies of the subsequent role of β3-AR activation in the cardiovascular disease process.
J Clin Cardiol, 2022, Volume 3, Issue 2, p47-50 | DOI: 10.33696/cardiology.2.034Cardiac Amyloidosis: A Survey of Current Awareness, Diagnostic Modalities, Treatment Practices, and Clinical Challenges Among Cardiologists in Selected Middle Eastern Countries
Cardiac amyloidosis (CA) is a progressive disease affecting the normal cardiac structure and function. CA could be isolated or associated with a spectrum of organ involvement, including the kidneys, lungs, nervous systems, bones, and others.
J Clin Cardiol, 2022, Volume 3, Issue 2, p51-59 | DOI: 10.33696/cardiology.2.035Effects of Anastomotic Angles and Distances of the Bypass Graft to the Stenosis on Blood Flow Hydrodynamics in a Bypass Grafting Coronary Artery
It is believed that the proper distance between the grafting location and the stenosis location and the appropriate angle of graft or transplantation in the blocked artery of the heart are two important factors in the removal or decrease of reappearance and re-development of intimal hyperplasia (IH), blood clotting, and re-blockage of the surgical artery. In the present study, a 3-D geometry of the host coronary artery as non-elastic with 75% symmetric axial cross-sectional area reduction is considered.
J Clin Cardiol, 2022, Volume 3, Issue 2, p60-70 | DOI: 10.33696/cardiology.2.036Looking Ahead: Interesting Developments in Menopause Management
There are many exciting developments in the field of midlife women’s health which explain how menopause symptoms, particularly hot flashes, may be an important vital sign and predictor of future health status
Paradoxical Low Flow Aortic Stenosis: A Clinical Dilemma
Internists as well as cardiologists often receive echocardiogram reports which failed to offer a clear definition of the aortic stenosis (AS) severity due to discordant data regarding the aortic valve gradients and the valve area. Sometimes AS appears severe according to the valve area criteria, in spite of the fact that gradients across the valve are not in the severe range.
Generating Awareness and a Planned Multidisciplinary Treatment Approach Can Save Both the Sight and Life in Retinoblastoma in Developing Countries
While rare, retinoblastoma is the most common (1:16000 – 18000 live births) intraocular and life threatening tumor of childhood [1,2]. According to the World Health Organization (WHO), 66% of children present with symptoms before 2 years of age and 95% before 5 years of age. About 8000 new cases are detected annually with the highest incidence in Africa and India. In fact, more than 1400 cases each year are from India [3].
Early Onset Fetal Growth Restriction: Does Path to Diagnosis Impact Outcomes and Pathology?
The etiology of fetal growth restriction is rooted in inadequate maternal-placental vascular malperfusion (MVM) of the placenta. Risk factors for MVM are broad and include maternal, fetal, and placental antecedent determinants.
Prognosis and Survival of Medullary Carcinoma of the Breast
Medullary breast carcinoma (MBC) is a rare tumor, representing 3% to 5% of invasive breast carcinomas. The World Health Organization defines it as a well-circumscribed invasive tumor, composed of poorly differentiated cells, arranged in sheets, without gland formation and a scarce collagen stroma with the presence of a very prominent lymphoplasmacytic infiltrate.
Role of Topical Insulin in Venous Ulcer Management
Wound healing is a dynamic process whereby cellular structures and the tissue layers are reconstructed. Adult wound healing can be categorized into three stages: inflammatory phase, proliferative phase, and remodelling phase. Blood cells like macrophages, neutrophils, extracellular matrix and mediators, various proteins, and various genes play an important role in these phases.
Machine Learning for Healthcare: Emerging Challenges and Opportunities in Disease Diagnosis
Diagnosis is a process that identifies, explains, or establishes the individual’s disease from its symptoms and signs. Early and precise diagnosis is crucial since it influences the efficacy of treatment and avoids longterm complications for the infected person. Further, in the case of infectious diseases, undiagnosed patients can transmit the disease to a healthy population unknowingly. Besides, most of the diseases evolve with the time that significantly affects the clinical outcomes.
Multidirectional Benefits of Nanotechnology in the Diagnosis, Treatment and Prevention of Tuberculosis
Despite the curious advancement in medical science and therapeutics, tuberculosis (TB) persist the primary factor of mortality than any other infectious disease and socioeconomic disaster for millions of people around the world. According to the World Health Organization (WHO), World’s One-third of the population is infected with this disease and of these, 8 to 10 million people develop active disease and 2 million people die each year and the rest of the infected people remain asymptomatic.
Evaluation and Management of chronic Hypertension in Pregnancy
Chronic hypertension is present in 1-2% of pregnant women. Women with chronic hypertension are at an increased risk of maternal and perinatal complications when compared with normotensive women.
Challenges Regarding the Management of Gynecological and Obstetric Complications in Women with Inherited Factor XIII Deficiency
The medical care of patients with inherited bleeding disorders requires a greater understanding and attention, especially in women who can be exposed to specific hemorrhagic complications such as menorrhagia or complications during pregnancies and deliveries.
Classical Drug and its New Role in COVID-19 Management
COVID-19 is the new emerging viral infection that already cause global public health problem [1-3]. More than 220 countries/territories are already attacked and there are more than 17 million patients around the world
Critical Appraisal OF Cervical Pregnancy Management
For a long time, it was rare to see a case of cervical pregnancy (CP) throughout the journey in the field of obstetrics. Recently, the circumstances showed dramatic changes and I think not uncommonly every one elsewhere in the field may face this problem to some extent and the CP term strikes his/her ears.
The Clinical Utility of Outpatient Continuous Glucose Monitoring in Establishing Insulinoma Diagnosis in a Patient with Impaired Nocturnal Hypoglycemia Awareness
Insulinomas are insulin secreting tumors arising from spontaneous mutations of the ductal, acinar, or islet cells of the pancreas. They are rare, having an incidence of only four cases per million people per year. Patients typically present with fasting hypoglycemia, experiencing neurologic symptoms like confusion, changes in vision, or abnormal behavior and autonomic symptoms like palpitations, diaphoresis, or tremulousness.
Adnexal Torsion During the Second Trimester of Pregnancy: Mc Burney Incision and Management Strategy
A 33-year-old pregnant woman at 26 weeks gestation presented with abdominal pain in the right iliac fossa. She had a history of a left ovarian cyst. The current pregnancy was normal. The patient was apyretic.
Progress in Diagnosis and Treatment of Immune Checkpoint Inhibitor-Associated Cardiotoxicity
Immune checkpoint inhibitors (ICIs) are a new type of broad-spectrum antitumor drugs, which mainly include cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) inhibitors, programmed cell death protein-1 (PD-1) and its ligand PD-L1 inhibitors. Since 2011, ICIs have been approved for more than 20 kinds of malignant tumors.
Sonoreperfusion Therapy for Microvascular Obstruction: A Review
Coronary artery disease and acute myocardial infarction are a leading cause of morbidity and mortality. Contemporary therapy is percutaneous coronary intervention (PCI), performed by balloon angioplasty and stent placement.
Congenital Diaphragmatic Hernia: An Update on Management Strategies and Outcomes
Congenital diaphragmatic hernia (CDH) is a severe developmental anomaly with an estimated global prevalence at birth of about 2.3 in 10,000 live births. Despite recent advances in antenatal diagnosis, fetal interventions and postnatal management, the condition continues to have a high mortality due to pulmonary hypoplasia and pulmonary hypertension and affected infants can suffer long-term morbidity. In a prospective national population cohort study from the United Kingdom and Ireland,
Management of Appendiceal Neuroendocrine Tumors: Beyond Tumor Size
In 1987, Charles Moertel and colleagues published a landmark series on 150 patients with appendiceal neuroendocrine tumors (ANET) that showed patients with tumors less than 2 cm in size had no evidence of regional or distant metastasis.
MicroRNA Signature Targeting Transient Receptor Potential Channels in the Prognosis and Therapy of Cancer
This short communication would to be the continuation of the Santoni’s paper entitled “Targeting Transient Receptor Potential Channels by MicroRNAs drives tumor development and progression” published in: Calcium Signaling, Advances in Experimental Medicine and Biology
Diagnosis and Management of Chorioamnionitis: A Case Report and Short Review of Literature
Chorioamnionitis is an unprecedented complication arising during labor and the intrapartum period which can lead to adverse outcomes in the mother such as sepsis and postpartum infections and the neonate such as stillbirth, neonatal sepsis, cerebral palsy, and delayed milestones with an increased NICU stay. Several studies have been done over the past years to study the pathophysiology and outcomes of chorioamnionitis.
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