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Journal of Experimental Neurology
ISSN: 2692-2819
Most Read Articles
Capillary Stalling: A Mechanism of Decreased Cerebral Blood Flow in AD/ADRD
Reece Crumpler , Richard J. Roman , Fan Fan
Alzheimer’s Disease (AD) and Alzheimer’s Disease-Related Dementias (ADRD) are debilitating conditions that are highly associated with aging populations, especially those with comorbidities such as diabetes and hypertension.
J Exp Neurol, 2021, Volume 2, Issue 4, p149-153 | DOI: 10.33696/Neurol.2.048
Impact of Cellular Senescence on Neurodegenerative Diseases during the COVID-19 Pandemic: Suitable Targets Required to Eliminate Cellular Senescence
Md Mohiuddin , Kazuo Kasahara
We recently reviewed the scientific literature that elucidates the impact of cellular senescence on COVID-19 complications.
J Exp Neurol, 2021, Volume 2, Issue 3, p140-142 | DOI: 10.33696/Neurol.2.046
Differential Fecal Microbiome Dysbiosis after Equivalent Traumatic Brain Injury in Aged Versus Young Adult Mice
Booker T Davis IV , Mecca B.A.R. Islam , Promi Das , Jack A Gilbert , Karen J. Ho , Steven J. Schwulst
Traumatic brain injury (TBI) has a bimodal age distribution with peak incidence at age 24 and age 65 with worse outcomes developing in aged populations
J Exp Neurol, 2021, Volume 2, Issue 3, p120-130 | DOI: 10.33696/Neurol.2.044
Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome
Shu-Hui Chuang , Ruth E. Westenbroek , Nephi Stella , William A. Catterall
Dravet syndrome (DS) is an intractable childhood epilepsy disorder affecting one in 15,000 to 20,000 births [1]. It is caused by de novo heterozygous lossof- function mutations in the SCN1A gene encoding the brain type-I voltage-gated sodium channel Nav1.1
J Exp Neurol, 2021, Volume 2, Issue 2, p81-85 | DOI: 10.33696/Neurol.2.040
Comparing Contrast Agent Enhancement: The Value of Artificial Intelligence/Machine Learning
Matthew J Kuhn MD , Julia W Patriarche PhD , Douglas Patriarche BSc , Massimo Bona MD , Miles A Kirchin PhD , Gianpaolo Pirovano
Gadolinium-based contrast agents (GBCAs) work by shortening the T1, T2, and T2* relaxation time constants of adjacent water protons in tissues.
J Exp Neurol, 2022, Volume 3, Issue 1, p8-14 | DOI: 10.33696/Neurol.3.055
Inhalational Anaesthetics: An Update on Mechanisms of Action and Toxicity
Jan Jedlicka , Philipp Groene , Julia Linhart , Elisabeth Raith , Davy Mustapha , Peter Conzen
Inhalational anaesthetics have been used for induction and maintenance of general anaesthesia for more than 150 years. In human medicine desflurane, sevoflurane, and isoflurane are commonly used.
J Exp Neurol, 2021, Volume 2, Issue 2, p62-69 | DOI: 10.33696/Neurol.2.037
Stroke, Oxygen and Prehospital Care: A Commentary on Current Treatments and Opportunities for Improvement
John Collins , Igor Rybinnik , Bryan Fischberg , Jonathan McCoy
Stroke is a common and very serious illness where timely evaluation and intervention can have dramatic effects on patient outcomes.
J Exp Neurol, 2021, Volume 2, Issue 1, p39-46 | DOI: 10.33696/Neurol.2.034
Caring for the Vulnerable and Disadvantaged
Sidonie E. Ibrikji MD , Shumei Man MD, PhD
Ischemic stroke carries a high readmission rate [1]. Among Medicare beneficiaries hospitalized for acute ischemic stroke, 14.1% were readmitted within 30 days, 29.2% within 90 days, and 55.3% within 1 year [1].
J Exp Neurol, 2022, Volume 3, Issue 1, p5-7 | DOI: 10.33696/Neurol.3.054
Alzheimers Disease: A Brief Review
Samantha McGirr , Courtney Venegas , Arun Swaminathan
The worldwide prevalence of dementia is estimated to be over 45 million people. Alzheimer’s disease (AD) is the most common cause of dementia, responsible for 60-80% of cases.
J Exp Neurol, 2020, Volume 1, Issue 3, p89-98 | DOI: 10.33696/Neurol.1.015
Skeletal Muscle Weakness Often Occurs in Patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)
Yves Jammes , Frédérique Retornaz
This commentary complements data reported in Clinical Biomechanics [1] reporting reduced maximal handgrip strength in numerous patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) in proportion to their lowered maximal physical performances.
J Exp Neurol, 2020, Volume 1, Issue 2, p35-39 | DOI: 10.33696/Neurol.1.007
Should Food Cravings be Controlled or Understood?
Jônatas de Oliveira , Ta´ki Athana´ssios Corda´s
Food Cravings (FC) is the term commonly used to describe sensations related to an intense desire for specific consumption [1], and there are features that we separate into internal and external aspects related to FC [2]
J Exp Neurol, 2020, Volume 1, Issue 2, p31-34 | DOI: 10.33696/Neurol.1.006