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Archives of Proteomics and Bioinformatics
ISSN: 2767-391X
Volume 4, Issue 1, p1-5
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Assessing Different Diagnoses in MIMIC-IV v2.2 and MIMIC-IV-ED Datasets
This study aims to reveal some important insights into the different diagnoses that are listed in Medical Information Mart for Intensive Care (MIMIC) dataset. This dataset includes patients from diverse backgrounds, ethnicity, demographics, etc. The diagnosis records are stored electronically using ICD-09 and ICD-10 codes. It is found that most of the patients were diagnosed at least once for essential hypertension and other related diseases.
Arch Proteom and Bioinform, 2024, Volume 4, Issue 1, p1-5 | DOI: 10.33696/Proteomics.4.014Chest Pain in Repeated Emergency Department Visitors
Chest pain is the leading symptom in 5 to 8% of all emergency department (ED) visits and is also one of the major reasons of repeated ED visits, causing around 6% of these cases [1]. Generally, in 15 to 25% of patients with chest pain, acute myocardial infarction (AMI) is the underlying cause.
Preliminary Study Assessing the Efficiency of a New Singleuse Obstetrical Vacuum Device: Icup2®
A national perinatal survey in France in 2016 showed that 12.2% of women have instrumentally assisted vaginal births with vacuum extraction used in 49.8% of cases, making it the most frequently used form of obstetrical assistance.
Reduced BCR Signaling and a Metabolic Shift Accompanies Malignant Progression of Follicular Lymphoma: A Lesson from Transcriptomics
Lymphoma represents the most common form of hematological malignancy in the developed world, accounting for 3.6% of all cancers and 55.6% of all blood cancers in Europe, with non-Hodgkin lymphomas (NHL) representing 90% of cases.
A View on the Contribution of Hedgehog Signalling to Ventricular Septal Development
The ventricular septal defect (VSD) is the most frequent congenital heart disease in humans. It is defined as an opening in the septum separating the left and the right ventricle. This gap results in a mixture of oxygenated and deoxygenated blood and in an enhanced blood flow towards the lung and the left ventricle, a condition that leads to severe diseases such as left ventricular hypertrophy as well as pulmonary edema and dilatation.
Evaluation and Management of chronic Hypertension in Pregnancy
Chronic hypertension is present in 1-2% of pregnant women. Women with chronic hypertension are at an increased risk of maternal and perinatal complications when compared with normotensive women.
Late ECG Changes after Cisplatin-Based Chemotherapy in Testicular Cancer Survivors
Introducing cisplatin-based therapy into testicular cancer treatment represents a substantial progress in therapy leading to a longer survival of patients and less adverse effects; currently it represents the standard therapy.
Commentary on: Echocardiography in Pulmonary Arterial Hypertension: Is It Time to Reconsider Its Prognostic Utility?
Pulmonary Arterial Hypertension (PAH) represents a rare but devastating disease due to small pulmonary arterial vessels remodelling and increased pulmonary vascular resistance leading to right ventricular dysfunction, right heart failure and death.
What is the Time Necessary to be Able to Place Transpedicular Screws According to the Chosen Technique?
Transpedicular screw placement techniques are technically plaintiffs have relied on navigation intraoperative which is limited by its high cost, limited use of a fluoroscope with the radiological overexposure of the personnel of health and patient offers limited help when placing screws, and vertebral anatomical modifications especially in patients with degenerative pathology result an index of placement-related complications suboptimal of the screws [1,2].
Since its introduction by Roy-Camille [3] and Louis [4] in the seventies, the use of screws pedicle has increased markedly to the present day
Weight and Abdominal Adiposity Loss with Auricular Acupuncture – A Randomized Controlled Trial
According to the WHO, obesity has more than doubled since 1980 [1]. The reality, however, is that most of the world’s population live in places where overweight and obesity kill more people than underweight. In 2016, more than a third of adults worldwide were classified as overweight or living with obesity, as were 41 million children younger than 5 years [2].
Integrating Neurology and Psychiatry throughout Educational Curricula for Healthcare Professionals
We recently reviewed the scientific literature linking dopamine agonist pharmacotherapy for neurological disorders to the development of impulsive and compulsive spectrum disorders (ICSDs).
Plasma Levels of Secretory Calreticulin among HIV Infected Patients in Bauchi State
Human immunodeficiency virus (HIV) is a lentivirus that causes HIV infection and over time acquired immunodeficiency syndrome. The objective was to evaluate plasma levels of Calreticulin (CALR) in HIV positive and negative individuals.
Case Report of Pulmonary Embolism with Right Ventricular Strain in a Young Female
Acute pulmonary embolism (PE) is when one or more thrombus travel to the lungs and obstruct the pulmonary artery or one of the branches of the pulmonary tree, producing signs and symptoms immediately after the obstruction. Saddle pulmonary embolism (SPE) is a rare type of acute PE that can lead to hemodynamic instability and death. The incidence of pulmonary embolism increases with age. In women, the risk of PE increases with pregnancy, hormonal contraceptives, and hormone replacement therapy.
A Rare Endoscopic Finding: Gastric Diverticulum
A 40-year-old man received upper gastrointestinal endoscopic scan during a health check-up. There was no history suggestive of Helicobacter pylori eradication, reflux esophagitis, peptic ulcer disease and upper abdominal surgery. Endoscopy revealed a wide-mouthed diverticulum of the size of 1.5 × 2 cm between the fundus and greater curvature of the stomach (Figure 1).
Epithelial Mesenchymal Transition: The Ultimate Driver of Cancer on Difficult Paths
Metastasis is the perilous aspect of cancer and is responsible for 90% of deaths due to cancer. It represents an enigmatic and complex biological cascade that is poorly understood. The constant development in cancer research and the advent of new principles in metastasis have discovered some of the molecular keystones like epithelial-mesenchymal transition (EMT) and cancer stem cells (CSCs) of this cascade.
EASI Monitoring: An Alternative to Conventional Electrocardiography in the Recording of Ventricular Tachycardia
This study compares the EASI monitoring setting with the conventional 12-lead electrocardiogram (ECG) in patients experiencing ventricular tachycardia (VT) episodes. The results revealed that the EASI monitoring setting demonstrated a VT morphology that closely resembled that of the conventional ECG in the majority of cases. This finding suggests that EASI monitoring could serve as a valuable alternative in situations where obtaining a conventional ECG is either risky or not feasible.
Diagnosis and Treatment of Normal Pressure Hydrocephalus and Repeated Subdural Hematoma and Effusion after Ventriculoperitoneal Shunt in the Elderly: A Case Report
Idiopathic normal pressure hydrocephalus (iNPH) is a special type of hydrocephalus that is characterized by cognitive decline, gait disturbance, and urinary incontinence. It can lead to dementia and bedridden within 1-3 years. Without surgical treatment in time, the prognosis was bleak. We report an iNPH case misdiagnosed with Alzheimer’s disease, with a disease course of 3 years.
Aldosterone Synthase Inhibitors for Treatment of Hypertension and Chronic Kidney Disease
Aldosterone excess is known to worsen hypertension and kidney function. Three selective aldosterone synthase inhibitors (ASIs) were evaluated in 3 phase 2 trials. In the first study, the ASI baxdrostat 2 mg orally once daily decreased systolic blood pressure (SBP) by 11.0 mmHg compared with placebo after 12 weeks in patients with treatment-resistant hypertension. In the second study including patients with uncontrolled hypertension, placebo-corrected reduction in SBP with lorundrostat 50 mg once daily was 9.6 mmHg after 8 weeks.
Intermittent Pre-Syncope after Surgical Correction of Aortic Stenosis Caused by Left Ventricular Outflow Obstruction by Elongated Mitral Leaflets
Left ventricular outflow obstruction (LVOTO) is a potential complication following surgical replacement of the aortic valve. We present an 88-year-old man who experienced periodic episodes of pre-syncope following aortic valve replacement. The underlying cause was identified as LVOTO resulting from elongated mitral valve leaflets. The diagnosis was established using stress echocardiography, which detected transient LVOTO with moderate rise in heart rate.
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