Editors' Choice | Journal of Experimental Neurology

In the Mind of the US Olympic Athletes; Longevity Advantage and Its Relation to Nervous System Disorders and Mental Illness

Moi Yamazaki, Jean-François Toussaint, Juliana Antero

In a recent study of 8124 US Olympic athletes, Antero et al. [1] found that the US Olympic athletes live 5 years longer than their general counterparts.

J Exp Neurol, 2022, Volume 3, Issue 1, p20-23 | DOI: 10.33696/Neurol.3.058

A Rodent Lumbosacral Spinal Cord Injury Model Reflecting Neurological and Urological Deficits of Humans

Behnaz Afrashteh, Karin Roider1, Sophina Bauer, Lukas Lusuardi, Patrick Heimel, David Hercher, Ludwig Aigner, Esra Keller

Spinal cord injury (SCI) to the terminal segments of the spinal cord causes severe disruption of the neural circuitry of the bladder, resulting in neurogenic underactive bladder (nUAB). We developed a rodent lumbosacral injury model to investigate the effects of bladder function and structure.

J Exp Neurol, 2022, Volume 3, Issue 2, p24-34 | DOI: 10.33696/Neurol.3.059

Commentary Open Access

Commentary: Use of BACTRAC Proteomic Database-Uromodulin Protein Expression During Ischemic Stroke

Gabriella-Salome K. Armstrong, Jacqueline A. Frank, Christopher J. McLouth, Ann Stowe, Jill M. Roberts, Amanda L. Trout, Justin F. Fraser, Keith Pennypacker

Uromodulin (UMOD) is a glycoprotein expressed by the epithelial cells of the thick ascending limb of Henle’s loop in the kidney. Research has shown that increased uromodulin expression may be associated with lower risk of cardiovascular disease in adults.

J Exp Neurol, 2021, Volume 2, Issue 1, p29-33 | DOI: 10.33696/Neurol.2.032

Commentary Open Access

Should Food Cravings be Controlled or Understood?

Jônatas de Oliveira, Ta´ki Athana´ssios Corda´s

Food Cravings (FC) is the term commonly used to describe sensations related to an intense desire for specific consumption [1], and there are features that we separate into internal and external aspects related to FC [2]

J Exp Neurol, 2020, Volume 1, Issue 2, p31-34 | DOI: 10.33696/Neurol.1.006

Commentary Open Access

Skeletal Muscle Weakness Often Occurs in Patients with Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS)

Yves Jammes, Frédérique Retornaz

This commentary complements data reported in Clinical Biomechanics [1] reporting reduced maximal handgrip strength in numerous patients with myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) in proportion to their lowered maximal physical performances.

J Exp Neurol, 2020, Volume 1, Issue 2, p35-39 | DOI: 10.33696/Neurol.1.007

Research Article Open Access

Discovery of New Candidate Genes for Anorexia Nervosa through Integration of eQTLs with Summary Statistics

Ting Wang, Jiahao Qiao, Haimiao Chen, Ping Zeng, Lihong Huang

Anorexia nervosa (AN) is a neuropsychic syndrome characterized by restriction of energy intake relative to requirements, abnormally low body weight and fear of weight gain, resulting in extreme emaciation and even death [1].

J Exp Neurol, 2022, Volume 3, Issue 2, p39-48 | DOI: 10.33696/Neurol.3.061

Commentary Open Access

Commentary to the Newly Rising Aquatic Exercise: Ai Chi

Pei-Hsin Ku, Johan Lambeck, Nai-Chen Yeh, Ray-Yau Wang

As aquatic therapy has become an important rehabilitative option, more exercise programs have emerged. Ai Chi, is one of the therapeutic aquatic exercise concepts with growing potential.

J Exp Neurol, 2020, Volume 1, Issue 3, p73-79 | DOI: 10.33696/Neurol.1.013

Review Article Open Access

Alzheimer and It’s Possible Therapy: A Review

Ashok Chakraborty, Anil Diwan

It is one of the most prevalent neurodegenerative disorder in the world, first described by a German Scientist, Alois Alzheimer, in 1906.

J Exp Neurol, 2020, Volume 1, Issue 4, p115-122 | DOI: 10.33696/Neurol.1.019

Short Communication Open Access

The Odyssey of Alpha-synuclein and Neuroinflammatory Mediators as Potential Candidates in the Aetiology of Parkinsons Disease

Jeswinder Sian-Hulsmann, Peter Riederer

The neurodegenerative disorder Parkinson’s disease (PD) is hallmarked by the presence of cytoplasmic inclusions, Lewy body (LB) and ravaged dopaminergic neurons in the substantia nigra pars compacta (SNc).

J Exp Neurol, 2020, Volume 1, Issue 4, p138-147 | DOI: 10.33696/Neurol.1.022

Commentary Open Access

Body Iron Overload is a Determining Factor in Brain Damage in Acute Ischemic Stroke

Joan Ramón Torrella, Ramón Rama

Stroke is the second largest cause of death worldwide, with a world annual mortality incidence of about 5.5 million people, and it is also the leading cause of disability worldwide with 50% of survivors being chronically disabled.

J Exp Neurol, 2021, Volume 2, Issue 4, p143-148 | DOI: 10.33696/Neurol.2.047

Research Article Open Access

Testing the Efficacy of Minocycline Treatment in an Awake, Female Rat Model of Repetitive Mild Head Injury

Rosemarie Hightower, Eric Brengel, Sophia Prom, Praveen Kulkarni, Craig F Ferris

Minocycline is being tested in clinical trials for the treatment of stroke and traumatic brain injury. As an antibiotic it reduces microglia activation. Can minocycline be used to treat mild repetitive head injury? To that end, minocycline was tested in a novel, closed-head, momentum exchange model of repetitive mild head injury in female rats impacted while fully awake. Magnetic resonance imaging (MRI) revealed there was no brain damage or contusion attesting to the mild nature of the head impacts in this model.

J Exp Neurol, 2024, Volume 5, Issue 3, p145-161 | DOI: 10.33696/Neurol.5.097