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Journal of Experimental Neurology
ISSN: 2692-2819
Most Cited Articles
Cathepsin D: A Candidate Link between Amyloid β-protein and Tauopathy in Alzheimer Disease
Caitlin N. Suire, Malcolm A. Leissring
Alzheimer disease (AD) is a debilitating neurodegenerative disorder characterized by extracellular deposition of the amyloid β-protein (Aβ) and intraneuronal accumulation of the microtubule-associated protein, tau
J Exp Neurol, 2021, Volume 2, Issue 1, p10-15 | DOI: 10.33696/Neurol.2.029
Commentary on Vulnerability and Resilience to Activity- Based Anorexia and the Role of Dopamine
Jeff A. Beeler, Nesha S. Burghardt
Anorexia nervosa (AN) is an eating disorder characterized by a fear of gaining weight and self-starvation, leading to life-threatening weight loss [1]. It occurs predominately in women and frequently begins during adolescence.
J Exp Neurol, 2021, Volume 2, Issue 1, p21-28 | DOI: 10.33696/Neurol.2.031
Stroke, Oxygen and Prehospital Care: A Commentary on Current Treatments and Opportunities for Improvement
John Collins, Igor Rybinnik, Bryan Fischberg, Jonathan McCoy
Stroke is a common and very serious illness where timely evaluation and intervention can have dramatic effects on patient outcomes.
J Exp Neurol, 2021, Volume 2, Issue 1, p39-46 | DOI: 10.33696/Neurol.2.034
Glutaminergic Signaling in the Nucleus Accumbens Modulates the Behavioral Response to Acute and Chronic Methylphenidate
Thomas Ming, Nachum Dafny
Methylphenidate (MPD) is a psychostimulant that is widely used to treat attention deficit hyperactivity disorder, and is being increasingly misused as a recreational drug and cognitive enhancer
J Exp Neurol, 2021, Volume 2, Issue 1, p49-61 | DOI: 10.33696/Neurol.2.036
Inhalational Anaesthetics: An Update on Mechanisms of Action and Toxicity
Jan Jedlicka, Philipp Groene, Julia Linhart, Elisabeth Raith, Davy Mustapha, Peter Conzen
Inhalational anaesthetics have been used for induction and maintenance of general anaesthesia for more than 150 years. In human medicine desflurane, sevoflurane, and isoflurane are commonly used.
J Exp Neurol, 2021, Volume 2, Issue 2, p62-69 | DOI: 10.33696/Neurol.2.037
Combined Antiseizure Efficacy of Cannabidiol and Clonazepam in a Conditional Mouse Model of Dravet Syndrome
Shu-Hui Chuang, Ruth E. Westenbroek, Nephi Stella, William A. Catterall
Dravet syndrome (DS) is an intractable childhood epilepsy disorder affecting one in 15,000 to 20,000 births [1]. It is caused by de novo heterozygous lossof- function mutations in the SCN1A gene encoding the brain type-I voltage-gated sodium channel Nav1.1
J Exp Neurol, 2021, Volume 2, Issue 2, p81-85 | DOI: 10.33696/Neurol.2.040
Alzheimers Disease: A Brief Review
Samantha McGirr, Courtney Venegas, Arun Swaminathan
The worldwide prevalence of dementia is estimated to be over 45 million people. Alzheimer’s disease (AD) is the most common cause of dementia, responsible for 60-80% of cases.
J Exp Neurol, 2020, Volume 1, Issue 3, p89-98 | DOI: 10.33696/Neurol.1.015
Alzheimer and It’s Possible Therapy: A Review
Ashok Chakraborty, Anil Diwan
It is one of the most prevalent neurodegenerative disorder in the world, first described by a German Scientist, Alois Alzheimer, in 1906.
J Exp Neurol, 2020, Volume 1, Issue 4, p115-122 | DOI: 10.33696/Neurol.1.019
Differential Fecal Microbiome Dysbiosis after Equivalent Traumatic Brain Injury in Aged Versus Young Adult Mice
Booker T Davis IV, Mecca B.A.R. Islam, Promi Das, Jack A Gilbert, Karen J. Ho, Steven J. Schwulst
Traumatic brain injury (TBI) has a bimodal age distribution with peak incidence at age 24 and age 65 with worse outcomes developing in aged populations
J Exp Neurol, 2021, Volume 2, Issue 3, p120-130 | DOI: 10.33696/Neurol.2.044
The Spread of Spectrin in Ataxia and Neurodegenerative Disease
Jon S. Morrow, Michael C. Stankewich
Experimental and hereditary defects in the ubiquitous scaffolding proteins of the spectrin gene family cause an array of neuropathologies
J Exp Neurol, 2021, Volume 2, Issue 3, p131-139 | DOI: 10.33696/Neurol.2.045
Capillary Stalling: A Mechanism of Decreased Cerebral Blood Flow in AD/ADRD
Reece Crumpler, Richard J. Roman, Fan Fan
Alzheimer’s Disease (AD) and Alzheimer’s Disease-Related Dementias (ADRD) are debilitating conditions that are highly associated with aging populations, especially those with comorbidities such as diabetes and hypertension.
J Exp Neurol, 2021, Volume 2, Issue 4, p149-153 | DOI: 10.33696/Neurol.2.048
A Protocol for the Generation of Treatment-naïve Biopsy-derived Diffuse Intrinsic Pontine Glioma and Diffuse Midline Glioma Models
Matt C. Biery, Alyssa Noll, Carrie Myers, Shelli M. Morris, Conrad A. Winter, Fiona Pakiam, Bonnie L. Cole, Samuel R. Browd, James M. Olson, Nicholas A. Vitanza
Diffuse intrinsic pontine glioma (DIPG) is an aggressive brain tumor that arises in the ventral pons during middle childhood.
J Exp Neurol, 2020, Volume 1, Issue 4, p158-167 | DOI: 10.33696/Neurol.1.025