Wound healing is a dynamic process whereby cellular structures and the tissue layers are reconstructed. Adult wound healing can be categorized into three stages: inflammatory phase, proliferative phase, and remodelling phase. Blood cells like macrophages, neutrophils, extracellular matrix and mediators, various proteins, and various genes play an important role in these phases.

Gastrointestinal (GI) disorders are common, also in persons with diabetes mellitus (DM), and can substantially impact their quality of life. In a representative sample of adults living in the United States, 25.8% of individuals with DM also reported disordered bowel habits and 14.6% experienced chronic constipation [3]. Others have reported an even higher prevalence of constipation of around 30% among patients with DM. While, in some patients, symptoms can be relieved with lifestyle and dietary modifications, many individuals with DM rely on the regular use of laxatives for the management

This is a commentary on the recent work by our group on fasting during Ramadan by young people with diabetes which was published as ISPAD Clinical Practice Consensus Guidelines. In this commentary, themes of selected studies published following the guidelines release are highlighted.

Chronic, non-healing, or slow to heal wounds present a significant and growing health problem in the United States, with an estimated 6.5 million people affected, at an annual cost of US $20 billion, with the highest risk groups represented by the elderly and the increasing prevalence of lifestyle diseases such as diabetes and obesity.

The World Health Organization defines quality of life (QoL) as “the perception that an individual has of his life, in the context of the culture in which he lives, integrating personal goals, expectations and concerns, well-being and discomfort”.