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Journal of Nanotechnology and Nanomaterials
ISSN: 2692-630X
Volume 4, Issue 1, p1-37
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
The Methods of Analysis for Determination of Metformin and Glimepiride in Different Matrices
In this literature review, we will introduce pharmacology in addition to most of the up-to-date reported methods that have been developed for determination of important oral hypoglycemic drugs which are metformin and glimepiride in their pure forms, combined forms with other drugs, combined forms with degradation products, and in biological samples.
J Nanotechnol Nanomaterials, 2023, Volume 4, Issue 1, p1-10 | DOI: 10.33696/Nanotechnol.4.037A Comprehensive Review of DNA Origami Stabilization Techniques
In recent years, DNA has emerged as a powerful tool in the field of nanotechnology. The DNA origami technique is largely responsible for this, revolutionizing nanofabrication due to its controllability, precision, and ability to leverage DNA’s unique properties. The technique consists of folding a long, single-stranded DNA (called a scaffold strand) by binding it with shorter staple strands to create almost any shape desired.
J Nanotechnol Nanomaterials, 2023, Volume 4, Issue 1, p11-18 | DOI: 10.33696/Nanotechnol.4.038Natural and Forced Convection in Multi-Phasic Electrochemical Systems
Multi-phasic electrochemical systems such as electrolyzers or metal-air batteries are intimately linked to energy transition and are at the heart of new scientific advances and modern industrial development. The presence of gas phases, inherent to the processes, directly impacts the performance and stability of the systems.
J Nanotechnol Nanomaterials, 2023, Volume 4, Issue 1, p19-28 | DOI: 10.33696/Nanotechnol.4.039Promoting Carbon Dioxide Reduction via Operando Surface Reconstruction
It is of great significance to study the dynamic reconstruction effect in variously heterogeneous catalytic reactions, such as electrocatalysis, thermal catalysis, including photocatalysis. So, the atomic or electronic structure change of the catalyst during the reaction processes should be deeply explored to understand the nature of the exact active sites [1-5].
J Nanotechnol Nanomaterials, 2023, Volume 4, Issue 1, p29-32 | DOI: 10.33696/Nanotechnol.4.040Fire Risk Rating Assessment for Wood Specimens Coated with Flame Retardant
Chung's equations-II, -III, and -IV were applied to evaluate the fire risk and fire risk ratings of flame retardants. As an example, a wood specimen coated with a flame retardant was selected and tested using a cone calorimeter according to the ISO 5660-1 standard. The external heat flux was fixed to 50 kW/m2. Fire performance index-III used three variables to evaluate the initial fire risk:
J Nanotechnol Nanomaterials, 2023, Volume 4, Issue 1, p33-37 | DOI: 10.33696/Nanotechnol.4.041Prospective Evaluation of Effect of Metformin on Activation of AMP-activated Protein Kinase (AMPK) and Disease Control in a Sub-group Analysis of Patients with GI Malignancies
Observational studies have demonstrated association of metformin with reduced cancer incidence and mortality in multiple cancer types, including gastrointestinal (GI) malignancies. Anti-neoplastic effects of metformin are believed through many mechanisms including activation of AMP-activated protein kinase, which controls mammalian target of rapamycin (mTOR) growth regulatory pathway.
DNA Nanotechnology Engineered Vesicle for Mimicking Biomolecular Signaling
Bio-inspired strategy is kind of interesting to fabricate devices and perform dynamic operations [1]. Various devices have been made, such as airplane, radar and submarine. In life science, as the fundamental entity, million years’ evolution enables cell becomes the most successful functionality.
Exploiting Nanotechnology to Target Viruses
Infectious diseases caused by microorganisms of the most varied natures and by viral entities cause millions of deaths every year. Around the world, viral infections have impacted civilizations’ circumstances since the earliest times, including the current panorama of the SARS-CoV-2 pandemic known as coronavirus disease in 2019 (COVID-19). In this sense, in the last century,
Multidirectional Benefits of Nanotechnology in the Diagnosis, Treatment and Prevention of Tuberculosis
Despite the curious advancement in medical science and therapeutics, tuberculosis (TB) persist the primary factor of mortality than any other infectious disease and socioeconomic disaster for millions of people around the world. According to the World Health Organization (WHO), World’s One-third of the population is infected with this disease and of these, 8 to 10 million people develop active disease and 2 million people die each year and the rest of the infected people remain asymptomatic.
Green Nanotechnology: The Influence of Intermolecular and Supramolecular Interactions
In the last decade, the study of nanometer-scale particles has grown exponentially worldwide. This growth is due to the broad field of nanostructures applications, which, due to their dimensions in nanometric sizes, have new properties not found in micro and macro scale. These properties result from the increase in the ratio between the surface area and volume, and the nanostructures’ size directly influences these. Tolerance to temperature, variety of colors, changes in chemical reactivity,
Nanotechnology in Water Treatment: An Optimistic Perspective for the Near Future
Unequal access to drinking water and basic sanitation are old issues in Brazil and worldwide. Besides, this situation foments the proliferation of infectious parasitic diseases. Moreover, mainly in underdeveloped countries, it victimizes socioeconomically vulnerable people. The degree of water contamination analysis, usually by fecal matter, is made by the number of microorganisms present in the sample, including Escherichia coli or thermotolerant coliforms. In addition, several
Nanotechnology for Water Purification – Current Trends and Challenges
Environmental pollution is a significant concern in both developing and developed countries. The pollution load in the environment accumulates as a result of anthropogenic activity. Both organic and inorganic contaminants are hazardous to living things, and their incidence and persistence have risen dramatically in current years.
A Review on Nanotechnology: Applications in Food Industry, Future Opportunities, Challenges and Potential Risks
Nanotechnology is an evolving revolution with enormous promise in a variety of fields, including mechanics, medicine, and the food business. Nanoparticles owing to having greater surface area and enhanced rates of mass transfer seem to pose higher biological and chemical activities, penetrability, catalytic behaviour, enzymatic reactivity, and quantum
Metformin in Patients with Chronic Heart Failure
Heart failure affects 1-2% of the adult population in developed countries and the lifetime risk of a heart failure diagnosis is 20%. Patients with heart failure have markedly reduced life expectancy, physical capacity and quality of life. One-year all-cause mortality rates for heart failure patients range between 7 and 17% and the yearly hospitalization rate can be as high as 44%.
Can Mono- or Combination Therapy of Metformin with Cimetidine and Ibuprofen be a Promising Potential Therapy for Breast Cancer?
Metformin (MET), either alone or in combination with other drugs, has been considered a promising drug in cancer therapy. MET via activation of adenosine monophosphate-activated protein kinase (AMPK) signaling pathway and inhibiting the mammalian target of rapamycin (mTOR) mediates tumor proliferation. Moreover, as an antagonist of the histamine H2-receptor (H2R), cimetidine (CIM) is also attributed to several immune-stimulatory responses in non-immunogenic cancers.
A Short Commentary of Nanotechnology on Traditional Chinese Medicine
Nanotechnology is the art of science manipulating matter at the nanoscale about 1 to 100 nanometers, 10-9 nm ranging from a sheet of paper (100,000 nanometers thick) to a human hair (around 80,000-100,000 nanometers).
The Methods of Analysis for Determination of Metformin and Glimepiride in Different Matrices
In this literature review, we will introduce pharmacology in addition to most of the up-to-date reported methods that have been developed for determination of important oral hypoglycemic drugs which are metformin and glimepiride in their pure forms, combined forms with other drugs, combined forms with degradation products, and in biological samples.
A Comprehensive Review of DNA Origami Stabilization Techniques
In recent years, DNA has emerged as a powerful tool in the field of nanotechnology. The DNA origami technique is largely responsible for this, revolutionizing nanofabrication due to its controllability, precision, and ability to leverage DNA’s unique properties. The technique consists of folding a long, single-stranded DNA (called a scaffold strand) by binding it with shorter staple strands to create almost any shape desired.
Fire Risk Rating Assessment for Wood Specimens Coated with Flame Retardant
Chung's equations-II, -III, and -IV were applied to evaluate the fire risk and fire risk ratings of flame retardants. As an example, a wood specimen coated with a flame retardant was selected and tested using a cone calorimeter according to the ISO 5660-1 standard. The external heat flux was fixed to 50 kW/m2. Fire performance index-III used three variables to evaluate the initial fire risk:
Is MGMT Gene Silencing an Opportunity for Enhanced Metformin Action in Glioblastoma cells?
Isocitrate dehydrogenase 1 (IDH1)-wild type glioblastoma (GBM) constitutes about 12-15% of primary central nervous system tumors. The 5-year survival remains dismal at less than 5% due to the limited options available in the management of GBM patients. Metformin (N, N-dimethyl biguanide), a medication used primarily in the management of patients with type 2 diabetes mellitus, showed anti-proliferative actions in the management of various tumor cells, including GBM. The temozolomide (TMZ)-based genotoxic management of GBM patients elicits DNA damage response (DDR) pathways that limit the efficacy of TMZ and induce resistance.
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