Loading
Archives of Obstetrics and Gynaecology
ISSN: 2692-787X
Volume 5, Issue 1, p1-47
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Sexual Abuse of Minors: 63 Cases at Mouila Regional Hospital in Gabon in 2022
Sexual abuse of a minor is defined as any sexual violation or act of a sexual nature committed against a human being under the age of eighteen, by violence, coercion, threat, surprise, or deception [1]. Similarly, rape of a minor is any act of sexual penetration of any kind committed against a human being under the age of eighteen using violence, coercion, threats, or deception [1].
Arch Obstet Gynecol, 2024, Volume 5, Issue 1, p1-5 | DOI: 10.33696/Gynaecology.5.056Use of Algorithms to Predict Disease in Obstetrics: A Clinical Perspective
Artificial Intelligence (AI) has been the subject of many contributions to the lay and professional literature in the past few years. While it may seem that the medical benefits of its use are immense, there may be reasons to consider a degree of caution in this regard. In particular, the clinical value of using algorithms to predict disease should be measured against the cases in which such algorithms are not used. Then, the resultant costs can be measured to show possible clinical benefit of AI.
Arch Obstet Gynecol, 2024, Volume 5, Issue 1, p16-17 | DOI: 10.33696/Gynaecology.5.058Bacterial Diversity in Placentas from Complicated Pregnancies Using 16s rRNA Gene Sequencing
Introduction: The ‘sterile womb paradigm’ is currently under debate and the advent of next generation 16S rRNA gene sequencing is driving the characterization of microbes associated with the amniotic cavity during pregnancy. Objective: To characterize the bacterial diversity in placentas from preterm and term births using next generation 16S rRNA gene sequencing in association with adverse pregnancy outcomes and histopathology studies.
Comparison and Analysis of Cerebroplacental Ratio and Umbilicocerebral Ratio in the Prenatal Diagnosis and Severity Assessment of Fetal Growth Restriction: A Retrospective Study and Systematic Review
Purpose: Doppler flow parameters of fetal umbilical artery (UA) and middle cerebral artery (MCA) have been widely used for fetal growth restriction (FGR), but their diagnostic efficacy remains contentious. The purpose of this study is to clarify the superiority of cerebroplacental ratio (CPR) and umbilicocerebral ratio (UCR) in terms of their correlation and predictive accuracy in diagnosing FGR.
Arch Obstet Gynecol, 2024, Volume 5, Issue 1, p33-39 | DOI: 10.33696/Gynaecology.5.060Harnessing Technology to Revolutionize Personalized Therapies for Metrorrhagia
Background: Metrorrhagia is defined as irregular uterine bleeding occurring between normal menstrual cycles. Unlike normal menstruation, metrorrhagia is irregular in frequency, duration, and volume. Understanding the etiology of metrorrhagia requires reviewing the hormonal regulation of the normal menstrual cycle.
Arch Obstet Gynecol, 2024, Volume 5, Issue 1, p40-47 | DOI: 10.33696/Gynaecology.5.061After Surgical Menopause, Should Menopausal Hormonal Therapy Started Only Before the Age of 45 Years?
The published study Compliance and health consequences of menopausal hormonal therapy after surgical menopause: A retrospective study in Thailand showed that menopausal hormonal therapy soon after bilateral oophorectomy before the age of natural menopause in Thailand
Artificial Intelligence and Machine Learning in Cancer Care: Current Applications and Future Perspectives
Cancer is the second most common cause of death worldwide, accounting for an estimated 9.6 million deaths in the year 2018, a number that is expected to grow to more than 13 million by 2030. In the past decade, we have witnessed unprecedented scientific advancement in the understanding of cancer etiology, prevention, diagnosis and development of new therapeutic strategies.
The Role of Anemia in Term and Preterm Pregnancies: Evidence from the Brazilian Multicenter Study on Preterm Birth (EMIP)
Evaluate the prevalence of anemia in term and preterm pregnancies and compare maternal and perinatal outcomes among groups.
Artificial Intelligence in Pharma: Positive Trends but More Investment Needed to Drive a Transformation
Over the past few years, pharmaceutical R&D has become aware of the potential benefits of leveraging artificial intelligence and its collective subfields including machine learning, deep learning, data science and advanced analytics.
Strong Association Between Placental Pathology and Second-trimester Miscarriage
The survival probability of early human conceptions is very low. At least 73% of natural single conceptions have no real chance of surviving six weeks of gestation [1]. After six weeks, survival rates improve rapidly as 90% of the remainder will survive to term.
Tenofovir at the Crossroad of the Therapy and Prophylaxis of HIV and HBV Infections
Tenofovir, alias (R)-PMPA, was first divulged as an anti- HIV agent in 1993 [1]. That it would in 2012, become the first antiretroviral agent, approved by the US FDA (Food and Drug Administration) to prevent HIV infection, could have been predicted from the findings of Tsai et al.
Archives of Gastroenterology Research: A Message from Prof. Dr. Rolf Teschke (Editor-in-Chief)
As the new editor-in-chief of Archives of Gastroenterology Research (AGR) I cordially welcome all current readers of AGR and future contributors to AGR. Together with my editorial team of AGR we encourage scientists and clinicians involved in the care of patients with gastrointestinal diseases to submit their interesting reports to AGR with the aim to be published following fair evaluation by external peer reviewers
Primary Lymph Node Kaposi's Sarcoma in Two HIV Positive Patients Presenting with Generalized Lymphadenopathy and Pancytopenia in a Third Level Hospital in Guatemala
We present two unique cases in which two HIV positive patients with generalized lymphadenopathy and pancytopenia without any skin lesions were diagnosed with primary lymph node Kaposi´s Sarcoma after excisional biopsy of an inguinal lymph node.
CCR5 Inhibitors and HIV-1 Infection
Cellular components are attractive targets for antiviral therapy because they do not mutate as readily as do viral proteins do [1-3]. The identification of CCR5 as an HIV-1 coreceptor [4-7], facilitated by the discovery of the antiviral activities of CCR5 ligand ?-chemokines [8], resulted in the development of new viral entry inhibitors to block CCR5 binding, including both- small molecules and CCR5 antibodies
Recent Progress in Preclinical HIV-1 Vaccine Research
Since isolation in humans in 1983 [1,2], HIV-1 has developed into a global pandemic. But an effective HIV-1 vaccine has not been succeeded despite multiple human vaccine trials performed [3,4]. Challenges to an effective vaccine arise from intrinsic virological and immunological features of HIV-1 [3-8].
Anti-HIV-1 Activity of Crocodylus mindorensis (Philippine Crocodile) Serum in Cell-free and Cell-associated Virus Interactions to Human Peripheral Blood Mononuclear Cells
Highly-Active Antiretroviral Therapy (HAART) is the recommended treatment and management strategy for HIV infection. Although the existing antiretroviral drugs are indispensably significant in improving the quality and extending the lives of HIV/ AIDS individuals, the drugs still have many limitations including development of resistance, production of toxicity, and their limited availability.
Assessment of Attitudes toward HIV and AIDS among Undergraduate Students at a Historically Black University
HIV is no longer only a public health challenge, but also a global threat with a devastating negative impact that has claimed over 35 million lives globally. In 2017, about 36.9 million people live with HIV, and 1.8 million people becoming newly infected with the disease globally [1].
Health Workers’ Perspectives on the Outcomes, Enablers, and Barriers to the Implementation of HIV “Test and Treat” Guidelines in Abuja, Nigeria
HIV/AIDS continues to be a major public health disease accounting for 35 million deaths across the world. In 2016 alone, there were 1.8 million new HIV infections and 1 million deaths worldwide.
HIV-1 Treatment Failure among Population Taking Antiretroviral Therapy in Ethiopia
For more than 35 years, the world has grappled with an AIDS epidemic that has claimed an estimated 35.0 million [28.9 million-41.5 million] lives and at its peak threatened global stability and security.
Development of an Ultrasensitive HIV-1 DNA Detection Assay Based on an Automated πCode End-Point PCR System
Currently, around 60-75% of the HIV positive patients in developed countries on anti-retroviral therapy (ART) have undetectable plasma viral load using current diagnostic PCR assays.
Patient-Reported Health Outcomes among HIV-Infected Patients on Antiretroviral Therapy in a Tertiary Hospital in Dar Es Salaam, Tanzania: A Cross Sectional Study
The use of antiretroviral therapy (ART) has resulted into HIV-infected patients living longer than it was the case in the pre-ART era [1]. Surviving patients are concerned not only with the treatment ability to extend their lives but also that their quality of life is improved on the course.
Black Women's Contribution to the HIV/AIDS Fight
After thousands of years of gender conflicts, the world now stands at the beginning of the feminine era, when women will rise to their proper standing, and the entire world will experience the harmony between men and women.
Use of Humanized Mouse Models for Studying HIV-1 Infection, Pathogenesis and Persistence
Different humanized mouse models have been introduced to enable HIV-1 research in vivo, which has been made possible by the development of immunodeficient mouse strains.
Metabolic Syndrome in HIV Infected Children Receiving Free HAART at a Centre of Excellence in HIV Care in Northern India
Implementation of Highly Active Antiretroviral Therapy (HAART) for patients with HIV has led to the dramatic reduction in AIDS related mortality in both children and adults [1]. With their longer life expectancy and improved quality of life, effects of ageing and other environmental factors are predisposing them to non-AIDS related morbidities, with cardiovascular diseases emerging as an important threat.
Unveiling an Atypical Response to HIV-1 Infection by the Patient Carrier of the Beta-S Globin Gene and Duffy Antigen Gene Double Mutation
It is known and well documented that genetic selective pressures occur from Plasmodium falciparum, P. vivax or P. knowlesi infection of red blood cells, such led to the selection of their cell membrane antigens, hemoglobin and enzymes thus associated to several mutation including, among others.
Scientific Archives is a global publisher initiated with the mission of ensuring equal opportunity for accessing science to research community all over the world. Spreading research findings with great relevance to all channels without any barrier is our goal. We want to overcome the challenges of Open Access with ensured quality and transparency.