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Journal of Physical Medicine and Rehabilitation
ISSN: 2690-0297
Volume 6, Issue 1, p1-13
Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
A Commentary on "Electroacupuncture Attenuates Ketamine-Induced Neuronal Injury in the Locus Coeruleus of Rats through Modulation of the CAMK II/CREB Pathway"
The research article entitled “Electroacupuncture (EA) attenuates ketamine-induced neuronal injury in the locus coeruleus of rats through modulation of the CAMK II/CREB pathway” makes a substantial contribution to our comprehension of the neuroprotective effects associated with EA. In this commentary, our objective is to intricately expand upon the discourse initiated by the focal article, scrutinizing recent advancements in the field and subjecting pivotal issues to critical analysis.
J Phys Med Rehabil, 2024, Volume 6, Issue 1, p1-4 | DOI: 10.33696/rehabilitation.6.038Changes in Obesity Prevalence Following Spinal Cord Injury: A Retrospective Review of Body Mass Index
Background: The prevalence of obesity is high in individuals with spinal cord injury (SCI) due to the alterations in body composition that occur as a direct result of injury. Body mass index (BMI) is used to classify body habitus. In 2009, an adjusted BMI classification, with lower thresholds for obesity, was recommended for individuals with SCI. Objective: Determine obesity prevalence before and after SCI to examine the trajectory of obesity development.
J Phys Med Rehabil, 2024, Volume 6, Issue 1, p5-13 | DOI: 10.33696/rehabilitation.6.039Therapeutic Values of Ketamine for COVID-19-Cared Patients: An Expert’s Point of View
Ketamine has long been used in the field of anesthesia [1]. Its rapid and long-acting analgesic effects associated with its dissociative properties have also established its use in prehospital and emergency department patients.
Multidisciplinary Acute Care of Central Retinal Artery Occlusion with a Stroke Paradigm: A Call to Action
Central retinal artery occlusion (CRAO) is a painless ophthalmologic emergency with potential for irreversible vision loss. Similar to ischemic stroke, CRAO occurs when there is sudden obstruction of the central retinal artery, leading to ischemic injury to the retina and subsequent cell death. Continuous occlusion and ischemia of the retina progresses to permanent damage to retinal cells and loss of vision.
Generating Awareness and a Planned Multidisciplinary Treatment Approach Can Save Both the Sight and Life in Retinoblastoma in Developing Countries
While rare, retinoblastoma is the most common (1:16000 – 18000 live births) intraocular and life threatening tumor of childhood [1,2]. According to the World Health Organization (WHO), 66% of children present with symptoms before 2 years of age and 95% before 5 years of age. About 8000 new cases are detected annually with the highest incidence in Africa and India. In fact, more than 1400 cases each year are from India [3].
Flat Grounding by Consciousness of Plantar Triangle with Decreased Impact
In recent years, various discussions, disagreements and opinions are seen in the field of athletics. For example, in long distance such as marathon, the recommended way of running has changed. In other words, it has been said that landing with the heel is good before, but recently there is some information that the first-class runner is landing on the toe
Body Mass Index and Treatment Response in Patients with Cardiac Light-Chain Amyloidosis
Elevated body mass index (BMI) has been associated with an increased risk of cancer and has been shown to have a negative impact on survival in patients with breast, prostate, oral cancer, and leukemia. In plasma cell dyscrasias, obesity has not only been shown to be a risk factor for the development of multiple myeloma, but also has been associated with a higher rate of progression from monoclonal gammopathy of unknown significance (MGUS) to multiple myeloma, and if intervened on, has bee
Energy Expenditure and Nutrition in Neurogenic Obesity following Spinal Cord Injury
Worldwide, obesity is a public health concern and a metabolic ailment characterized by excessive adipose tissue accumulation resulting from an imbalance of energy expenditure and energy intake [1]. This disorder is a known risk factor for cardiovascular disease, type 2 diabetes mellitus, dyslipidemia, hypertension, and metabolic
Improving Obesity and Insulin Resistance by Targeting Skeletal Muscle MKP-1
Obesity has reached a global epidemic and it predisposes to the development of insulin resistance, type 2 diabetes and related metabolic diseases. Current interventions against obesity and/or type 2 diabetes such as calorie restriction, exercise, genetic manipulations or established pharmacological treatments have not been successful for many patients with obesity and/or type 2 diabetes.
Obesity, Family History of Diabetes, and Consanguineous Marriages are Risk Factors among Urban Population in South Indian City of Bengaluru
In 2017, approximately 424.9 million adults (age 20- 79 yrs) were affected by diabetes, with 4 million deaths. Global diabetes burden is estimated to increase up to 628.9 million people. Moreover, diabetes care costed approximately $727 billion in 2017.
Viable but Nonculturable Gastrointestinal Bacteria and Their Resuscitation
Viable but nonculturable (VBNC) bacteria are deeply dormant phenotypic variants that are characterized by a loss of culturability in conventional culture media, yet retain some viability markers. Thus, low metabolic activity, nutrient uptake, membrane integrity, and respiration are all detectable in these dormant cells. In 1982, the VBNC state was first described for Escherichia coli and Vibrio cholerae. Shortly afterwards, VBNC Salmonella enteriditis were found to regain culturability
The Health Effects of the Abuse of Ketamine
Addiction is defined as being a primary chronic disease of the brain reward, motivation, and memory in this complex circuitry. A dysfunction in this complex circuitry can lead to certain manifestations in an individual [1]. The individual who suffers from addiction does not have the ability to abstain from this harmful pursuit and, as a result,
Polycyclic Aromatic Hydrocarbons and Mammary Cancer Risk: Does Obesity Matter too?
Breast cancer is the most commonly diagnosed cancer in women in the United States. Breast cancer incidence rates, particularly among younger women, have been increasing since the 1930s, and are only partially explained by changes in parity, age at first birth, and improved screening and detection. Many questions remain unanswered regarding the mechanisms that underlie current risk.
The Role of the Sciatic Nerve Ultrasound Elastography in the Clinical Pathway: A Meta-analysis
Ultrasound elastography is a diagnostic method, to measure elasticity and strain in tissues and organs. The aim of this review was to highlight the usefulness of sciatic nerve ultrasound elastography in clinical practice. Different changes affect the sciatic nerves through various diseases and conditions.
Continuing Medical Education Rarely Addresses Leading Public Health Problems Including Diabetes and Obesity
Medical schools sponsor continuing medical education (CME) to help fulfill their mission of improving the health of the community. CME programs can help physicians stay up-to-date with the best practices associated with disease prevention and treatment.
To Quell Childhood Obesity: The Pacific Ending Childhood Obesity Network’s Response
The need to accelerate collective and concerted action to combat Non-Communicable Diseases (NCDs) and childhood obesity is particularly relevant in the Pacific context.
From Silos to Solidarity: Case Study of a Patient-Centered, Integrative Approach to Opioid Tapering and Chronic Pain Mitigation in a Multidisciplinary AIDS Clinic
Chronic pain, defined as pain lasting longer than three months, is a significant public health burden and has been associated with depression, anxiety, poor quality of life and opioid use disorder (OUD).
Commentary on Once-Weekly Semaglutide in Adults with Overweight or Obesity
Obesity is an undertreated global epidemic that increases morbidity and mortality by causing widespread harm to multiple organ systems. Severe obesity or obesity with associated comorbidities warrants a comprehensive treatment approach including lifestyle modifications plus either bariatric surgery or prescription medications.
Commentary on Lahiri et al. Weight and Body Mass Index Change After Switching to Integrase Inhibitors or Tenofovir Alafenamide Among Women Living with HIV
Among women living with HIV (WLWH), increases in body weight and body mass index (BMI, kg/m2) have been observed after switching to the antiretroviral therapies (ART) - Integrase Inhibitors (INSTI) and/or Tenofovir Alafenamide (TAF).
Body Mass Index and COVID-19: Likely Causes for Obesity and Undernutrition Correlation with Disease Severity
Coronaviruses are one of the viruses causing the common cold, a disease that has never had a cure nor any effective prevention. They form are a large family of enveloped, positive-sense, single-stranded RNA viruses that infect a broad range of vertebrates, and for which bats are believed to be an important reservoir.
The Effect of Diet Induced Obesity on Serotonin in Zebrafish
Obesity is a worldwide epidemic and a major risk factor for numerous diseases. The regulation of feeding behavior and body weight depends on a wide range of neuronal pathways influencing satiety and hunger. Serotonin (5-HT) is one of those players identified to have a profound effect on energy homeostasis. The effect of obesity on 5-HT metabolism in the gastrointestinal (GI) tract and its underlying mechanisms still needs to be further elaborated.
The Impact of Fluid Resuscitation Timeliness in Geriatric Patients with Sepsis: A Single Center Retrospective Cohort Study
Sepsis is a key driver of worldwide mortality, representing close to 20% of global deaths in 2017 [1]. Approximately half of patients hospitalized with sepsis are 65 years and older [2]. Delivery of 30ml/kg of crystalloid fluid bolus within three hours of diagnosing sepsis remains a cornerstone of the Surviving Sepsis Campaign (SSC)
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