Case Report Open Access
Volume 3 | Issue 2 | DOI: https://doi.org/10.33696/Neurol.3.063

Nonarteritic Anterior Ischemic Optic Neuropathy (NAION) Induced by Selective Agonist of Serotonin 5-HT1 Receptor – A Case Report

  • 1Department of Neurology, Beneficência Portuguesa Hospital of São Paulo, São Paulo, Brazil
  • 2Department of Neuroradiology, Beneficência Portuguesa Hospital of São Paulo, São Paulo, Brazil
  • 3Department of Neuro-ophthalmology, The Beneficência Portuguesa Hospital of São Paulo, São Paulo, Brazil
+ Affiliations - Affiliations

Corresponding Author

Barbara Maini de Carvalho, barbamaini@outlook.com.br

Received Date: August 08, 2022

Accepted Date: October 20, 2022


Introduction: Ischemic optic neuropathies are prevalent diseases and important cases of vision loss. In particular, non arteritic ischemic optic neuropathy (NAION) is the most common cause of optic neuropathy after 50 years of age and the etiology of NAION involves risk factors from the patients and some drugs as triggers, like triptans, selective agonists of 5-HT1 receptors. The use of triptans also has few associations with NAION in the literature, making the report of this case important to improve the clinical suspicion of this entity on migraine patients and highlights the importance of correct use of these medications.

Case report: We report a case of a 50-year-old woman with no cardiovascular risk factors. She had a history of seven consecutive days of migraine attacks and abuse of triptans. Two days after improving her headache and keep taking Naratriptan, she awoke in the morning with unilateral painless altitudinal visual deficit, with neurological and fundoscopic examination compatible with NAION.

Conclusion: This case is important to show us the correlation of migraine and ischemic optic neuropathy, but also to show the correlation of triptans, used for migraine treatment, with NAION.


Optic neuropathy, Triptans, Migraine, Case report

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