Journal of Experimental Neurology

Commentary Open Access

Integrating Psychotherapy into Clinical Care for Individuals with Parkinson’s Disease

Andreas-Antonios Roussakis , Rima Hawkins , Cara Mackley , Paola Piccini

Psychotherapy has historically played a limited role in Parkinson’s disease (PD) care, despite the high prevalence of neuropsychiatric and psychological conditions in this population. With sporadic evidence for the benefits of psychotherapy in PD, a clear pathway for psychotherapeutic intervention is still in development.

Commentary Open Access

A Commentary on “Suppressive Effect of Topical Moxifloxacin on Imiquimod-Induced Model of Psoriasis in Mice”

Alaa Hamza Abbas

The Journal of Experimental Neurology frequently highlights studies that bridge the gap between neurological disorders and systemic conditions, particularly those with an immunological component. The recent article, "Suppressive Effect of Topical Moxifloxacin on Imiquimod-Induced Model of Psoriasis in Mice," by Abbas et al., presents intriguing data suggesting a potential role for the fluoroquinolone antibiotic moxifloxacin in the treatment of psoriasis, a chronic inflammatory skin disorder.

Commentary Open Access

From Atmospheric Forecasting to Neurological Inspiration: The Emerging Role of Brain Emotional Learning in Environmental Modeling

Alireza Hakimi

The intersection of computational neuroscience and environmental modeling has birthed novel algorithms that emulate brain-inspired emotional learning. One such contribution is the BELBFM (Brain Emotional Learning Based on Basic and Functional Memories) model, recently proposed for dual-height wind speed forecasting. While designed for meteorological applications, the structure and function of BELBFM echo principles long studied in neurobiology.

Review Article Open Access

Extraforaminal Spinal Nerve Stimulation: A Practical Surgical Guide Based on Clinical Experience

Danielle Kohr , Alaa Abd-Elsayed , Sudhir Diwan , Michael Kugler

Extraforaminal spinal nerve stimulation (SNS) is an emerging neuromodulation technique for treating neuropathic pain. Targeting the spinal nerve distal to the intervertebral foramen enables anatomically precise stimulation, distinguishing it from conventional spinal cord or dorsal root ganglion stimulation. This article provides the first comprehensive description of the extraforaminal SNS approach, including technical refinements, anatomical insights, and clinical experience.

Case Report Open Access

Hypoplastic Internal Carotid Artery in a Young Stroke Patient

Farid Ullah , Muhammad Osama , Salman Khan , Imran Ullah , Abdullah , Aizaz Ali , Hafsa Salim

Hypoplastic internal carotid artery (HICA) is a rare congenital vascular anomaly, typically asymptomatic due to collateral circulation. However, in certain cases, it may present with ischemic stroke. We report a 17-year-old male with a history of smoking and illicit drug use who presented with acute left-sided weakness. Imaging revealed an infarct in the right middle cerebral artery territory and a hypoplastic right internal carotid artery.