Archives of Dentistry

Short Communication Open Access

The Health Effects of the Abuse of Ketamine

William James Maloney

Addiction is defined as being a primary chronic disease of the brain reward, motivation, and memory in this complex circuitry. A dysfunction in this complex circuitry can lead to certain manifestations in an individual [1]. The individual who suffers from addiction does not have the ability to abstain from this harmful pursuit and, as a result,

Research Article Open Access

Impact of Age on Prognostic Treatment Outcomes Among Oral Squamous Cell Carcinoma Patients: Evidence from Sri Lanka

Irosha Perera, N.S.S. Jayasuriya, H.G.H. Jinadasa, K.H.B. Kodituwakku, S. Kandegedara, A.M. Attygalla

Introduction: Disease free survival is the optimum treatment outcome in cancer management. We explored the impact of age on key treatment outcomes among a group of Sri Lankan oral squamous cell carcinoma patients. Material & Methods: We studied clinical records of 44 oral squamous cell carcinoma patients consisted of age- matched two groups (22 in each group) who had close surgical margins and clear surgical margins respectively. 

Letter to the Editor Open Access

Oral Lesions in the COVID-19 Positive Individuals – An Update

Ambreen Rehman, Ibrahim O. Bello, Ehsanul Hoque Apu

The novel Coronavirus Disease 2019 (COVID-19) is a highly contagious acute respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARSCoV- 2). Studies have reported oral lesions in patients with COVID-19 such as ulcers or blisters or diffuse reddish lesions affecting both keratinized and non-keratinized tissues of the oral cavity. Such lesions have been observed in the palate, lip mucosa, buccal mucosa, and tongue.

Research Article Open Access

The Role of Selected Habits, Periodontal Disease and Oral Hygiene Status on the Occurrence and Prognosis of Oral Mucosal Lesions

Sharika Gunathilake, Anil Welikanna, Suresh Sinnathamby, DSC Colombathanthri, GH Sueneth Chandima, Irosha Perera, Manosha L. Perera, Nadeena Jayasuriya, Sakuntha Ratnapreya

Background & Aim: Patients presenting with an array of benign oral mucosal diseases to oral & maxillofacial (OMF) units practicing risk habits such as betel chewing could be at high risk of poor oral health and progressing into Oral Potentially Malignant Disorders (OPMD) or oral cancer. Against this backdrop, we investigated the possible role of selected habits, periodontal disease an oral hygiene in occurrence and prognosis of oral mucosal lesions, among a cohort of patients in Sri Lanka.

Case Series Open Access

Chronic Oral Mucosal Trauma and Oral Cancer: A Series of Cases

Kobkan Thongprasom, Ekarat Phattarataratip

Oral mucosal lesions affect the quality of life of many patients and are an apparent indicator of oral and general health. Red or white lesions in the oral cavity, including asymptomatic ones should never be ignored. Dentist could be the first person performing important roles in the early diagnosis and management of oral lesions. Taking a biopsy should be considered to exclude the possibility of potentially malignant conditions or oral cancers.

Review Article Open Access

The Involvement of 18 kDa Translocator Protein (TSPO) in Cigarette Smoke-related Diseases: A Review

Nidal Zeineh, Abraham Weizman, Moshe Gavish

The 18 kDa translocator protein (TSPO) is mainly located in the outer mitochondrial membrane, widely spread throughout the body tissues and is abundant particularly in steroid-synthesizing organs. Cigarette smoke (CS) is considered as a major risk factor for the development of oral, lung, and cardiovascular diseases, as well as cancers. TSPO protein expression is elevated in cells exposed to CS, which subsequently results in increased TSPO-related cellular processes.