Oral mucosal lesions affect the quality of life of many patients and are an apparent indicator of oral and general health. Red or white lesions in the oral cavity, including asymptomatic ones should never be ignored. Dentist could be the first person performing important roles in the early diagnosis and management of oral lesions. Taking a biopsy should be considered to exclude the possibility of potentially malignant conditions or oral cancers. The aim of these series of cases is to present interesting clinical oral manifestations that demonstrate the relationship between oral hygiene, chronic irritation, dysplasia, and oral squamous cell carcinoma. Oral mucosal changes related to chronic trauma or irritation can greatly impact patient’s oral as well as general health.

Irritation; Mucosal trauma; Oral cancer; Squamous cell carcinoma