Cardiovascular disease (CVD) is one of the major causes of death worldwide and poses a huge public health burden [1,2]. Early identification of individuals at risk of cardiovascular disease is crucial to develop effective preventions. The DOHAD hypothesis proposed by Professor Barker et al. states that an abnormal environment

Revacept, a dimeric fusion protein of the extracellular domain of GPVI and the human Fc-fragment, inhibits collagen-mediated platelet adhesion and subsequent aggregation at the site of vascular injury. Finally, the possible utility of this pharmacological approach in the prevention of tumor metastasis is discussed.

Vinpocetine is a derivative of vincamine. It has been used to prevent and treat cerebrovascular disorders such as stoke and dementia, and remains widely available in dietary supplements that often marketed as nootropics. Due to its excellent safety profile at therapeutic dose regimen, vinpocetine has raised research interest in its new applications in various experimental disease models.

This commentary will address the salient points explored in a previous publication on the role of the red blood cell and platelet in the evolution of mammalian and avian endothermy, include additional concepts associated with the evolution of endothermy, and finally address future directions that may be followed in this area of research. The most simplistic definition of the terms endothermic and ectothermic is the former refers to warmblooded animals that maintain their body temperature by endogenous mechanisms while the latter refers to coldblooded animals that require external sources of heat to warm their bodies. In actuality the ability to maintain body heat is more complex for many animals categorized by these terms since some large-bodied ectotherms can maintain body temperatures by internal mechanisms and some endotherms do not maintain body temperature at selective times, such as when hibernating.

Health intelligence on the frequency of cardiovascular disease (CVD) and its risk factors identifies targets and populations for preventative strategies and allows evaluation of health outcomes, behaviors and interventions in populations and health care settings.