Abstract
Sarcoidosis is a systemic granulomatous disease that primarily affects adults, but it can also occur in the pediatric population, although less commonly. Common manifestations of sarcoidosis include pulmonary involvement, lymphadenopathy, and skin lesions. The clinical presentation in children can be diverse, making diagnosis challenging. Age-related variations in clinical features have been observed, with distinct manifestations in younger versus older children. We present a case of an 11-year-old boy who exhibited generalized maculopapular skin lesions and lymphadenopathy, which is atypical for pediatric sarcoidosis. The patient had a history of juvenile idiopathic arthritis (JIA). Laboratory evaluation revealed elevated serum angiotensin-converting enzyme (ACE), Histopathological examination of an excised lymph node confirmed the diagnosis. Treatment led to substantial improvement and resolution of symptoms. This case emphasizes the importance of considering sarcoidosis in the differential diagnosis of children presenting with skin lesions and lymphadenopathy. The diverse clinical manifestations of pediatric sarcoidosis underscore the need for further research to establish standardized management strategies for this population. Regular follow-up evaluations are necessary to monitor disease activity and manage potential long-term sequelae.
Keywords
Childhood sarcoidosis, Skin lesions, Lymphadenopathy, Juvenile idiopathic arthritis, Angiotensin-Converting Enzyme