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Commentary Open Access

Psychedelics: Historical Context, Emerging Science, and Future Clinical Frontiers

  • 1Institute of Human Behaviour and Allied Sciences, New Delhi, India
+ Affiliations - Affiliations

Corresponding Author

Vipul Janardan, vipuljanardan777@gmail.com

Received Date: September 03, 2024

Accepted Date: March 23, 2026

Abstract

Psychedelics a class of psychoactive compounds such as psilocybin, lysergic acid diethylamide (LSD), and dimethyltryptamine (DMT) are undergoing a scientific renaissance. Studies since 2020 have shown their therapeutic promise in mental health treatment. This Commentary synthesizes historical usage, current neuroscientific and clinical evidence, and explores ethical and regulatory frontiers for future medical integration. While showing efficacy in treatment-resistant depression, PTSD, and addiction, these substances require rigorous, ethically guided scientific validation.

Keywords

Psychedelics, Mental Health, Treatment, Psilocybin, Lysergic acid diethylamide, Dimethyltryptamine, Therapeutic benefits, Depression, Anxiety

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