Introduction: Gastrointestinal stromal tumors (GIST) account for 85% of all mesenchymal neoplasms of the digestive tract. Of these, two thirds are found in the stomach. GISTs usually present as small lesions, often incidentally discovered. On the other hand, the presence of an abdominal mass, a very infrequent finding, can produce symptoms: Abdominal pain, digestive bleeding, nausea, vomiting, in addition to weight loss and intestinal constipation.
Case Presentation: Male patient, 52 years old, asymptomatic, with progressive increase in abdominal volume for 5 years, attributed to beer ingestion. Eating normally, usual bowel rhythm and performing daily work activities. Studied by abdominal tomography that showed expansive formation, with some calcifications and hypodense areas of necrosis, lobulated, measuring 33.1 x 28.6 x 21.8 cm and occupying almost the entire abdominal cavity.
Conclusion: Giant gastric GIST are rare neoplasms and surgical R0 resection is the best therapeutic proposal.
Giant GIST, Surgical management, Gastrointestinal Stromal Tumors, Mitotic index