Background: Adenosquamous carcinoma is a rare colorectal carcinoma with glandular and squamous histologic components. The proximal colon is a rare site for Adenosquamous carcinoma as compared to lower gastrointestinal tract. To the best of our knowledge, only a few cases of Adenosquamous Carcinoma of the proximal colon have been reported in the literature till date, with the incidence being <0.1%.
Case Presentation: We present a case of an elderly female aged 58 years 7 months who presented with generalized pain abdomen and loss of appetite. Right hemicolectomy with Ileo-colic anastomosis was done for her. Histopathologic examination and subsequent immunohistochemistry revealed a Moderately Differentiated Adenosquamous Carcinoma of the Ascending Colon.
Conclusion: Adenosquamous carcinoma of the colon are rare and have a worse prognosis than conventional adenocarcinoma. Early detection and radical surgical excision are important and adjuvant therapy can be considered, for better survival of the patient
Adenosquamous carcinoma, Proximal colon, Hemicolectomy