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Journal of Experimental Pathology
ISSN: 2694-5061
Featured Articles
The Duration of Mechanical Ventilation is the Main Cause of Bacterial/Fungal Superinfection in Critically Ill Patients with COVID-19 at Altitude
Molano Franco Daniel, Masclans Joan R, Nuvials Xavier, Gomez Mario, Enciso Cesar, Villabon Mario, Beltran Edgar, Pérez Mauricio, Ramírez Gabriel, Gomez Andres, Escobar Luis, Villa Andres, Arias-Reyes Cristian, Soliz Jorge
The COVID-19 pandemic is associated with a large number of patients spending long periods of time in intensive care units (ICUs), many of them suffering bacterial/fungal superinfections. However, both the incidence and cause of bacterial/fungal superinfections in COVID-19 critically ill patients remain poorly investigated in hospitals located at high altitudes (above 2500 meters).
J Exp Pathol, 2022, Volume 3, Issue 2, p55-64 | DOI: 10.33696/pathology.3.040
News About the Extracellular Vesicles from Mesenchymal Stem Cells: Functions, Therapy and Protection from COVID-19
Jacopo Meldolesi
The present Commentary is a critical follow-up of a previous review about “Extracellular vesicles, news about their role in immune cells: physiology, pathology and diseases”, appeared in Clinical and Experimental Immunology last June 2019 [1].
J Exp Pathol, 2021, Volume 2, Issue 1, p47-52 | DOI: 10.33696/pathology.2.015
Succinate Accumulation Links Mitochondrial MnSOD Depletion to Aberrant Nuclear DNA Methylation and Altered Cell Fate
Kimberly L. Cramer-Morales, Collin D. Heer, Kranti A. Mapuskar, Frederick E.Domann
Epigenetic processes provide a mechanism for integrating metabolic inputs and translating them into various phenotypic outputs [1,2]. Indeed, epigenetic modifiers often require or are inhibited by key citric acid cycle (CAC) metabolites (e.g. succinate,
J Exp Pathol, 2020, Volume 1, Issue 2, p60-70 | DOI: 10.33696/pathology.1.009
Application of Encapsulated Probiotics in Health Care
Esmat Alemzadeh, Ahmad Oryan
Probiotics are generally defined as nonpathogenic living organisms that have beneficial effects on host health. The term “probiotic” means “for life” that is derived from Greek language. At first, probiotics was defined as substances that are produced with microorganisms and promote the other microorganisms.
J Exp Pathol, 2020, Volume 1, Issue 1, p16-21 | DOI: 10.33696/pathology.1.003
Endoscopic Ultrasound-Guided Liver Biopsy; the Pathologist’s Perspective
Naren Nallapeta, Deepthi Rao, Ahmad H. Ali, Neal Sharma, Jamal A. Ibdah, Ghassan M. Hammoud
In this study, the safety and efficacy of liver biopsies performed by endoscopic ultrasound (EUS-LB) were compared with those performed via the traditional percutaneous route at our Medical Center between January 2018 and August 2019.
J Exp Pathol, 2020, Volume 1, Issue 1, p1-10 | DOI: 10.33696/pathology.1.001
Mechanistic and Translational Advances Using iPSC-Derived Blood Cells
Christopher S Thom, Stella T Chou, Deborah L French
The human induced pluripotent stem cell (iPSC) technology was developed more than ten years ago and has provided important tools for the mechanistic and cellular interrogation of many diseases [1]. To generate iPSC lines, somatic cells are reprogrammed into cells resembling embryonic stem cells by the overexpression of key transcription factors.
J Exp Pathol, 2020, Volume 1, Issue 2, p36-44 | DOI: 10.33696/pathology.1.010