Journal of Clinical Cardiology

Review Article Open Access

Shaping the Future of Cardiac Wellness: Exploring Revolutionary Approaches in Disease Management and Prevention

Tamer A. Addissouky, Ibrahim El Tantawy El Sayed, Majeed M. A. Ali, Yuliang Wang, Ayman El Baz, Naglaa Elarabany, Ahmed A. Khalil

Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality worldwide. Effective prevention and management strategies are essential to reduce the burden of CVDs. This review summarizes recent advances in the prevention and management of CVDs. In terms of prevention, lifestyle modifications, such as diet, exercise, and smoking cessation, remain important strategies.

Research Article Open Access

Cardiac Amyloidosis: A Survey of Current Awareness, Diagnostic Modalities, Treatment Practices, and Clinical Challenges Among Cardiologists in Selected Middle Eastern Countries

Dania Mohty, Samer Nasr, Hany Ragy, Hasan Ali Farhan, Bahaa Fadel, Islam Alayary, Marcelle Ghoubar

Cardiac amyloidosis (CA) is a progressive disease affecting the normal cardiac structure and function. CA could be isolated or associated with a spectrum of organ involvement, including the kidneys, lungs, nervous systems, bones, and others.

Commentary Open Access

Commentary on: Peptidylglycine alpha-amidating Monooxygenase is Required for Atrial Secretory Granule Formation

Emil Daniel Bartels, Jens Peter Gøtze, Richard E. Mains, Betty A. Eipper

The electron-dense spherical granules found in the perinuclear region of atrial myocytes store and release both proatrial and probrain natriuretic peptides (proANP and proBNP, respectively). Mature ANP and BNP produce vasodilation and natriuresis and inhibit the renin-angiotensin and sympathetic nervous systems.

Commentary Open Access

Predicting COVID-19 Hospitalized Patients’ Outcome with Homocysteine

Giovanni Ponti, Marco Manfredini, Gabriella Oliva, Tomris Ozben, Caterina Fontana, Aldo Tomasi

The COVID-19 pandemic has provoked a global, rapid increase of cases due to the high infectivity of the etiological agent, COVID-19 virus. In February 2021, over 110 million confirmed COVID-19 cases with 1 million deaths were reported worldwide (www.who.int).

Review Open Access

Lipoprotein Apheresis: First FDA Indicated Treatment for Elevated Lipoprotein(a)

Anne K. Nugent, Jessica V. Gray, Lauryn K. Gorby, Patrick M. Moriarty

Lipoprotein(a) [Lp(a)] is a genetically determined lowdensity lipoprotein (LDL) particle that is comprised of apolipoprotein(a) [apo(a)] and apolipoprotein B-100 (apoB) moieties. It is well-established that elevated Lp(a) is an independent risk factor for cardiovascular disease (CVD).

Research Article Open Access

Chest Pain in Repeated Emergency Department Visitors

Ksenija Slankamenac, Michael Stucki, Dagmar I. Keller

Chest pain is the leading symptom in 5 to 8% of all emergency department (ED) visits and is also one of the major reasons of repeated ED visits, causing around 6% of these cases [1]. Generally, in 15 to 25% of patients with chest pain, acute myocardial infarction (AMI) is the underlying cause.