Journal of Clinical Cardiology

Original Research Open Access

Left Atrial Appendage Closure Patients with Same Day Discharge Versus Non-same Day Discharge: Demographics and Outcome Comparisons

Zayd Parekh , Rohan Mylavarapu , Emily Cox , Weihai Zhan , Imdad Ahmed

Currently, newer strategies are being implemented regarding WATCHMAN placement in the community hospital, such as same-day discharge (SDD). The safety of this protocol needs to be further assessed. The study aimed to evaluate the outcomes of SDD versus non-SDD in patients with nonvalvular atrial fibrillation who underwent WATCHMAN placement by comparing baseline demographics and post-procedure outcomes.

Review Article Open Access

Cardiac Remodeling Post-myocardial Infarction: Novel Therapies—Narrative Review

Faizan Wadood Siddiqui , Abieyuwa Tari-Ere Oshodin , Manahil Ali , Sherien Metry , Sheima Gaffar , Sawera Gul , Muhammad Ali Muzammil

Myocardial infarction (MI) leads to progressive left ventricular (LV) remodeling, significantly affecting patient outcomes and prognosis. This paper provides a critical overview of the current standard of care and emerging pharmacological and regenerative therapies for prevention of cardiac remodeling post-MI.

Original Research Open Access

Relationship Between Fluid Responsiveness and Outcome of Patients with Acute Heart Failure Reduced Ejection Fraction

Ratna Mariana Tamba , Andika Sitepu , Hilfan Ade Putra Lubis , Abdul Halim Raynaldo , Cut Aryfa Andra , Andre Pasha Ketaren , Yuke Sarastri

Higher left ventricular filling pressure (LVFP) is often associated with non-fluid responsiveness in heart failure patients, particularly those with reduced ejection fraction. This hemodynamic state has been linked to adverse outcomes, including higher rates of rehospitalization and mortality. However, the prognostic implications of fluid responsiveness assessed after decongestion remain uncertain.

Original Research Open Access

Clinical Safety and Procedural Performance of the Optima SC Semi-compliant Percutaneous Transluminal Coronary Angioplasty Balloon Catheter in Coronary Intervention: A Multicenter Post-Market Study

Chirag Jagdish Parikh , Anuj Sarda , Anup Ashok Pusate , Sujeet Narain

Semi-compliant (SC) balloons are essential in PCI for lesion preparation before stent deployment. The Optima SC PTCA balloon catheter, a next-generation device, was evaluated in this post-marketing, multicenter study to assess its real-world performance and safety.

Commentary Open Access

Ratio Variables in Regression: Implications for Cardiovascular Research

Zachary R. McCaw , Thomas W. Soare , Colm O’Dushlaine

Ratio variables, such as body mass index (BMI) and left ventricular ejection fraction (LVEF), are deeply ingrained in cardiovascular research and practice, yet the use of ratios in regression models can confuse associations and obscure underlying mechanisms.

Original Research Open Access

Association of Subretinal Drusenoid Deposits in Age-Related Macular Degeneration with Decreased Cardiac Performance and Systemic Perfusion in Severe Aortic Stenosis

Carlo Mannina , Liang Wang , Anton Camaj , Edgar Argulian , Sean Pinney , R Theodore Smith , Stamatios Lerakis

Subretinal drusenoid deposits (SDDs), a hallmark of age-related macular degeneration (AMD), have been linked to cardiovascular disease, but the underlying mechanism remains unclear. We investigated the association between SDDs and severe aortic stenosis (AS).

Original Research Open Access

Outcomes of Transcatheter Aortic Valve Replacement Performed Within 90 Days after Acute Myocardial Infarction: A Nationwide Retrospective Analysis

Muhammad Ali Elahi , Ahmed M. Younes , Ahmed K. Mahmoud , Ibrahim Kamel , Ahmed Hanfy , Marwan Saad , Islam Y. Elgendy

Transcatheter aortic valve replacement (TAVR) is currently the most commonly utilized management strategy for severe aortic stenosis. The short-term outcomes of TAVR in patients who experienced a recent acute myocardial infarction (AMI) remain unclear.

Case Report Open Access

Plasma Donation Inducing Acute ST-Elevation Myocardial Infarction: A Case Report

Alla Adelkhanova , Gustavo Espinoza Mercado , Bushra Urooj Ahmed , Inti Fernandez Hoyos , Aravind Kuchkuntla

Plasma donation is generally considered a safe procedure, and most reported adverse events are related to venipuncture or transient volume loss. Arterial thrombotic events, including acute myocardial infarction, are exceedingly rare but have been described after source plasma donation performed by plasmapheresis. 

Commentary Open Access

Communal Coping with Heart Failure: Commentary on Marital Quality and Patient Survival 

Michael J. Rohrbaugh

Earlier Am J Cardiol papers reported that a composite measure of marital quality predicted heart failure (HF) survival over follow-up intervals of 3 and 8 years after adjusting for baseline illness severity (NYHA class).