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Archives of Molecular Biology and Genetics
ISSN: 2831-6754
Allelic Variants on SLC6A3 Neurotransmitter Gene and Their Relationship with Personality Traits Scales in Egyptian Athletes
Human dopamine transporter gene (SLC6A3) is one of the neurotransmission genes that plays an important role in controlling the behavior and psychological reactions toward various physical activities. The aim of the present study is to evaluate the associations between SLC6A3 3’-UTR VNTR (3’VNTR) genotypes and eight personality traits in Egyptian athletes. One hundred athletes (50 males and 50 females) and one hundred non-athletes participated in this investigation either in individual or team games.
Arch Mol Biol Genet, 2023, Volume 2, Issue 1, p9-19 | DOI: 10.33696/genetics.2.012Risk Management Implemented by Turkey during the COVID-19 Pandemic Disaster
The coronavirus (COVID-19) outbreak occurred in China and spread to the whole world in a short period of time. The WHO (World Health Organization) named the viral disease as COVID-19 (Novel Coronavirus, SARS-CoV-2) on February 11, 2020.
Arch Mol Biol Genet, 2022, Volume 1, Issue 2, p69-83 | DOI: 10.33696/genetics.1.010SARS-CoV-2 Mutations, Diagnosis and Their Concern
The first case is described in Wuhan city of China in December 2019 and the disease (COVID-19) continues to pose threat to global health all over the world affecting more than approximately 476 million confirmed cases and 6 million deaths. Reliable and effective methods are taken a critical role such as real-time reverse transcriptase (RT)-PCR test as a gold standard method, serological tests, and reverse transcriptase loopmediated isothermal amplification (RT-LAMP) method is chosen firstly.
Arch Mol Biol Genet, 2022, Volume 1, Issue 2, p57-65 | DOI: 10.33696/genetics.1.008Impact of Sleep on Autophagy and Neurodegenerative Disease: Sleeping Your Mind Clear
Sleep is an evolutionarily conserved phenomenon which has survived tremendous evolutionary pressures. Its disruption has deleterious implications for human health. The importance of sleep is illustrated by the fact that sleep deprivation in many animals leads to death. While sleep is tightly regulated by a combination of intrinsic and extrinsic factors it becomes progressively disrupted in old age and in neurodegenerative diseases including Alzheimer’s disease (AD), frontotemporal dementia (FTD), Parkinson’s disease (PD) and Huntington’s disease (HD).
Arch Mol Biol Genet, 2022, Volume 1, Issue 2, p43-56 | DOI: 10.33696/genetics.1.007Commentary on NOBOX Mutations in Premature Ovarian Insufficiency
NOBOX is an ovarian specific transcription factor that plays an important role in follicular growth and survival. Nineteen NOBOX variants have been previously associated with premature ovarian insufficiency (POI). Disease severity in patients with heterozygous and homozygous mutations largely overlap however, hampering genotype-phenotype correlations. We recently reported the first case of biallelic truncating mutations (NM_001080413.3 (NOBOX):c.826C>T, p.(Arg276*) and NM_001080413.3(NOBOX):c.1421del, p.(Gly474Alafs*76)) of NOBOX in two Belgian sisters with POI.
Arch Mol Biol Genet, 2022, Volume 1, Issue 1, p29-33 | DOI: 10.33696/genetics.1.005The Nature of Radiation-induced Inherited Recessive Gene Mutations in Drosophila Melanogaster
The nature of gene mutations induced by ionizing radiation in germ cells and transmitted to offspring remains one of the most important problems in radiation genetics of higher eukaryotes. The data accumulated in this field were obtained by different authors under different experimental conditions which does not give a complete insight about the nature of radiation-induced inherited mutations at different genome levels (chromosome, gene, DNA).
Arch Mol Biol Genet, 2022, Volume 1, Issue 1, p12-19 | DOI: 10.33696/genetics.1.003Scientific Archives is a global publisher initiated with the mission of ensuring equal opportunity for accessing science to research community all over the world. Spreading research findings with great relevance to all channels without any barrier is our goal. We want to overcome the challenges of Open Access with ensured quality and transparency.