Archives of Dentistry

Short Communication Open Access

The Health Effects of the Abuse of Ketamine

William James Maloney

Addiction is defined as being a primary chronic disease of the brain reward, motivation, and memory in this complex circuitry. A dysfunction in this complex circuitry can lead to certain manifestations in an individual [1]. The individual who suffers from addiction does not have the ability to abstain from this harmful pursuit and, as a result,

Editorial Open Access

Does the Immediate Dental Implant Placement into Fresh Extraction Sockets Decrease the Marginal Bone Lose?

Ahmad Al Nashar

The insertion of dental implants immediately after teeth extractions has become a routine clinical procedure in implant dentistry. This treatment modality has received much attention and has shown favorable results [1-4]. Several studies have reported that successful osseointegration is possible when implants are inserted immediately

Original Research Open Access

Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study

Manosha L. Perera, Irosha Perera

Background/Aim: The relationship between Herpes Simplex Virus (HSV) and oral risk habits is still uncertain. This study aimed to investigate the connection between oral risk habits and HSV status in a group of male patients from Sri Lanka who have oral fibroepithelial polyps. Materials and methods: We collected 25 fibroepithelial polyps from nine oro-maxillofacial units in six provinces of Sri Lanka. Tissue samples were taken from frozen excisional biopsies to avoid contamination and tested for HSV- DNA using a real-time PCR assay. 

Commentary Open Access

Expression and Regulation of FNDC5/irisin in Periodontium and Dental Pulp

Yang Y, Reseland JE, Helen Pullisaar

Teeth together with supporting periodontium are continuously under physical stimulation in daily life and clinical dental situations. Physical stimulation plays an important role in oral health. However, the underlying molecular pathways by which physical stimulation preserves oral health remain unknown.

Research Article Open Access

A Clinical Audit on the Follow-up Rate and Endodontic Outcome of Root Canal Therapy Performed by Dental Undergraduates

Michelle Kher Wei Chua, Abhishek Parolia, Hey Chiann Wong, Siew Wei Tan, Zhi Meng Tan, Yuxuan Ooi, Wilson Wee Ser Seah, Allan Pau

To identify follow-up rate and evaluate the endodontic outcome and their association with technical quality of root canal therapy (RCT) done by dental undergraduates. Technical quality of RCT and follow-up rate visits of 350 teeth from 272 patients after RCT done by dental undergraduates were evaluated retrospectively from year 2012 to 2015 using the electronic records. These patients were recalled to assess the clinical, radiographic and overall endodontic outcome. Clinical and radiographic examinations were done following the criteria in compliance with standards guidelines. 

Review Article Open Access

The Involvement of 18 kDa Translocator Protein (TSPO) in Cigarette Smoke-related Diseases: A Review

Nidal Zeineh, Abraham Weizman, Moshe Gavish

The 18 kDa translocator protein (TSPO) is mainly located in the outer mitochondrial membrane, widely spread throughout the body tissues and is abundant particularly in steroid-synthesizing organs. Cigarette smoke (CS) is considered as a major risk factor for the development of oral, lung, and cardiovascular diseases, as well as cancers. TSPO protein expression is elevated in cells exposed to CS, which subsequently results in increased TSPO-related cellular processes.