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Archives of Dentistry

ISSN: 2689-6222

Original Research Open Access
Volume 6 | Issue 1 | DOI: https://doi.org/10.33696/dentistry.6.029

Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study

Manosha L. Perera1,*, Irosha Perera2
  • 1School of Dentistry and Oral Health, Griffith University, Queensland, Australia (Alumni)
  • 2Preventive Oral Health Unit, The National Dental Hospital (Teaching), Colombo, Sri Lanka
+ Affiliations - Affiliations

Corresponding Author

Manosha Lakmali Perera, manosha.perera@alumni.griffithuni.edu.au

Received Date: August 27, 2024

Accepted Date: November 25, 2024

Citation:

Perera ML, Perera IR. Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study. Arch Dent. 2024;6(1):5-10.


Copyright: © Perera ML, Perera IR. Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study. Arch Dent. 2024;6(1):5-10.

Abstract

Background/Aim: The relationship between Herpes Simplex Virus (HSV) and oral risk habits is still uncertain. This study aimed to investigate the connection between oral risk habits and HSV status in a group of male patients from Sri Lanka who have oral fibroepithelial polyps. 

Materials and methods: We collected 25 fibroepithelial polyps from nine oro-maxillofacial units in six provinces of Sri Lanka. Tissue samples were taken from frozen excisional biopsies to avoid contamination and tested for HSV- DNA using a real-time PCR assay. 

Results: The results showed that HSV-DNA was present in 44% of the samples, with 66.67% being HSV-1 and 33.33% being HSV-2. However, there was no significant association between HSV status and oral risk habits such as betel quid chewing, smoking, and alcohol abuse (p>0.05).

Conclusion: These findings suggest that the need for larger case-control studies to determine any significant associations between different types of Herpes Simplex Virus and oral risk habit.

Keywords

Herpes Simplex Virus, Oral Risk Habits, Asymptomatic, Latency

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Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study

Background/Aim: The relationship between Herpes Simplex Virus (HSV) and oral risk habits is still uncertain. This study aimed to investigate the connection between oral risk habits and HSV status in a group of male patients from Sri Lanka who have oral fibroepithelial polyps. Materials and methods: We collected 25 fibroepithelial polyps from nine oro-maxillofacial units in six provinces of Sri Lanka. Tissue samples were taken from frozen excisional biopsies to avoid contamination and tested for HSV- DNA using a real-time PCR assay. 

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