Archives of Dentistry

Short Communication Open Access

The Health Effects of the Abuse of Ketamine

William James Maloney

Addiction is defined as being a primary chronic disease of the brain reward, motivation, and memory in this complex circuitry. A dysfunction in this complex circuitry can lead to certain manifestations in an individual [1]. The individual who suffers from addiction does not have the ability to abstain from this harmful pursuit and, as a result,

Research Article Open Access

Impact of Age on Prognostic Treatment Outcomes Among Oral Squamous Cell Carcinoma Patients: Evidence from Sri Lanka

Irosha Perera, N.S.S. Jayasuriya, H.G.H. Jinadasa, K.H.B. Kodituwakku, S. Kandegedara, A.M. Attygalla

Introduction: Disease free survival is the optimum treatment outcome in cancer management. We explored the impact of age on key treatment outcomes among a group of Sri Lankan oral squamous cell carcinoma patients. Material & Methods: We studied clinical records of 44 oral squamous cell carcinoma patients consisted of age- matched two groups (22 in each group) who had close surgical margins and clear surgical margins respectively. 

Original Research Open Access

Herpes Simplex Virus and Oral Risk Habits in a Cohort of Sri Lankan Male Oral Fibroepithelial Polyp Patients: Findings from a Preliminary Study

Manosha L. Perera, Irosha Perera

Background/Aim: The relationship between Herpes Simplex Virus (HSV) and oral risk habits is still uncertain. This study aimed to investigate the connection between oral risk habits and HSV status in a group of male patients from Sri Lanka who have oral fibroepithelial polyps. Materials and methods: We collected 25 fibroepithelial polyps from nine oro-maxillofacial units in six provinces of Sri Lanka. Tissue samples were taken from frozen excisional biopsies to avoid contamination and tested for HSV- DNA using a real-time PCR assay. 

Research Article Open Access

Axiographic Plots: Interpretation and Diagnostic Interest

Latifa Zenati, Mahdia Ait Mehdi

Axiography allows the three-dimensional study of condylar movements in the perspective of diagnosis of cranio-mandibular dysfunctions (CMD) and real adjustment of the semi-adaptable articulator. Conceived by Cammpion in 1902, Robert Lee was responsible for updating this principle of study.

Letter to the Editor Open Access

Oral Lesions in the COVID-19 Positive Individuals – An Update

Ambreen Rehman, Ibrahim O. Bello, Ehsanul Hoque Apu

The novel Coronavirus Disease 2019 (COVID-19) is a highly contagious acute respiratory disease caused by severe acute respiratory syndrome coronavirus-2 (SARSCoV- 2). Studies have reported oral lesions in patients with COVID-19 such as ulcers or blisters or diffuse reddish lesions affecting both keratinized and non-keratinized tissues of the oral cavity. Such lesions have been observed in the palate, lip mucosa, buccal mucosa, and tongue.

Review Article Open Access

The Involvement of 18 kDa Translocator Protein (TSPO) in Cigarette Smoke-related Diseases: A Review

Nidal Zeineh, Abraham Weizman, Moshe Gavish

The 18 kDa translocator protein (TSPO) is mainly located in the outer mitochondrial membrane, widely spread throughout the body tissues and is abundant particularly in steroid-synthesizing organs. Cigarette smoke (CS) is considered as a major risk factor for the development of oral, lung, and cardiovascular diseases, as well as cancers. TSPO protein expression is elevated in cells exposed to CS, which subsequently results in increased TSPO-related cellular processes. 

Editorial Open Access

Photodynamic Therapy for the Prevention of SARS-CoV-2 Infection in Dental Office: Could be Possible?

Cinzia Casu

In January 2020, the World Health Organization (WHO) identified a novel coronavirus SARS-CoV-2 in the Wuhan province of China, which has since caused a worldwide pandemic, with more than 21.2 million confirmed cases and over 760,200 confirmed deaths as of 14 August 2020. SARS-CoV-2 is a single-stranded RNA virus classified in the family Coronaviridae.