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Case Report Open Access
Volume 7 | Issue 1 | DOI: https://doi.org/10.33696/casereports.7.037

Tracheal Pleomorphic Adenoma Masquerading as Uncontrolled Asthma

  • 1Department of Pulmonology, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal
  • 2Department of Pathology, Unidade Local de Saúde de Santa Maria, Lisbon, Portugal; Department of Pathology, CUF Oncologia; Faculty of Medicine, University of Lisbon, Gulbenkian Institute of Molecular Medicine, Portugal
+ Affiliations - Affiliations

Corresponding Author

Inês Spencer, inesmspencer@gmail.com

Received Date: August 04, 2025

Accepted Date: September 18, 2025

Abstract

Pleomorphic adenoma is a benign tumor typically found in the salivary glands. Its occurrence in the trachea is rare and often overlooked due to low clinical suspicion, despite respiratory symptoms. We report the case of a 47-year-old Caucasian woman, active smoker with a 34 pack-year history, and a diagnosis of non-allergic asthma for 15 years, with progressive worsening control despite medical therapy. The main clinical symptoms were dyspnea and recurrent respiratory infections. Imaging revealed a tracheal mass causing extensive luminal obstruction. The lesion was successfully treated with bronchoscopic excision and laser therapy. Histopathological and genetic analyses confirmed the diagnosis of pleomorphic adenoma. This case highlights the importance of considering neoplastic etiologies in patients with persistent respiratory symptoms unresponsive to standard asthma treatment.

Keywords

Bronchoscopic excision, Pleomorphic adenoma, Refractory asthma, Tracheal tumor

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