Leukemia is the most common childhood malignancy and is the most common cause of cancer death before the age of 20. Pediatric leukemia can be subdivided into acute versus chronic and lymphoid versus myeloid leukemia.

The concept of immunotherapy has been traced as far back to third century BC Qin dynasty in China through the purposeful inoculation of Variola minor to prevent smallpox. 

Traumatic dental injury (TDI) impacts the teeth and/or other hard and soft tissues within and around the mouth and oral cavity region [1]. TDI are very common across the globe leading to 85% of patients having injuries in the oral region [2] which was revealed by a meta-analysis conducted in 2018 [3]. TDIs are frequently presented as serious

The global scaling up of treatment and care for people living with Human Immunodeficiency Virus (PLHIV) has led to a 43% decline in new HIV pediatric infections since 2003, with 330,000 newly infected children in 2011.

Nonalcoholic fatty liver disease (NAFLD), a spectrum of pathologies ranging from simple steatosis to fibrosis and cirrhosis, is the most common cause of chronic liver disease, affecting over 80% of adults with obesity, one third of obese children ages 3-18 in North America [2] and ~10% of the general pediatric population.