Loading

Review Article Open Access

Embracing Neurodiversity: The Critical Role of Awareness And  Acceptance in Autism Spectrum Disorders

  • 1Senior Genetic Counselor & Associate Manager Medical Scientific affairs, Department of Clinical Genomics, Redcliffe Lab, Noida, Uttar Pradesh-201301, India
  • 2Genetic Counselor, Department of Clinical Genomics, Life Cell Diagnostics, Hyderabad, Telangana, 500072, India
+ Affiliations - Affiliations

Corresponding Author

Aayushi Gupta, Aayushigenomics@gmail.com

Received Date: November 04, 2024

Accepted Date: February 22, 2025

Abstract

This review provides a comprehensive overview of autism spectrum disorder (ASD), focusing on its early signs, clinical presentation, etiology, screening and diagnosis, therapeutic interventions, and the critical role of family support. ASD characterized by a range of challenges in social communication, behavior, and sensory processing, with symptoms manifesting in early childhood. While the exact causes remain unclear, a combination of genetic and environmental factors believed to contribute to its development. Early screening and diagnosis are essential for effective intervention, utilizing standardized tools and structured assessments to identify individuals at risk. Therapeutic approaches, such as Applied Behavior Analysis (ABA), speech therapy, and occupational therapy, are vital for enhancing communication skills and overall functioning. Additionally, family support plays a crucial role in promoting acceptance and understanding, fostering a nurturing environment that aids in the individual's development. Gene-environment interactions, including maternal stress and environmental toxins, influence neurodevelopmental disorders like ASD, with Sirtuin 1 (SIRT1) playing a key role in disease pathophysiology. Modulating SIRT1 through activators or inhibitors, along with targeting metabolic pathways, may offer new therapeutic strategies for ASD. This review also underscores the importance of awareness and advocacy in creating inclusive communities that support individuals with autism and their families, ultimately enhancing their quality of life and enabling them to reach their full potential.

Keywords

Autism spectrum disorder, Awareness, Diagnosis, Therapeutic approaches

Author Information X