Review Article Open Access
Volume 3 | Issue 2 | DOI: https://doi.org/10.33696/cancerimmunol.3.048

Dose-dependent Effects of Vitamin C on Cancer Regulation: A Review

  • 1Institute of Molecular Biology and Biotechnology, University of Lahore, Lahore, Pakistan
  • 2Allama Iqbal Medical College Lahore, Lahore, Pakistan
  • 3Services Hospital, Lahore, Pakistan
  • 4School of Medical Sciences, University of Bradford, Bradford, UK
+ Affiliations - Affiliations

Corresponding Author

Shabana Akhtar, s.akhtar133@bradford.ac.uk, shabana.akhtar@imbb.uol.edu.pk

Received Date: February 18, 2021

Accepted Date: May 20, 2021


Vitamin C is a part of cell physiology and is utilized in many metabolic reactions. Therapeutically, it was found useful in many ailments including fatal diseases such as cancer. It has ability to induce apoptotic pathway in cancer cells in order to kill them within the body at lower concentrations without affecting the non-cancerous cells. Antioxidant enzymes and reactive oxygen species are involved in the mechanism of initiation of apoptosis mediated by Vitamin C. Current review is highlighting the dose-dependent therapeutic potential of Vitamin C based upon the available literature.


Vitamin C, Health benefits, Cancer, Regulation, Chemotherapeutic

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