The manufacture of scaffolds for wound healing has become important, especially the formation of tissuespecific scaffolding. In order to create scaffolds, it is essential to mimic the chemical composition, physical morphology and biological functions of the human body. Scaffolds can be created by using synthetic polymers (e.g. polycaprolactone) or natural polymers (e.g. chitosan) or a combination of both. The addition of natural polymers can be very advantageous as they can avoid

Chronic, non-healing, or slow to heal wounds present a significant and growing health problem in the United States, with an estimated 6.5 million people affected, at an annual cost of US $20 billion, with the highest risk groups represented by the elderly and the increasing prevalence of lifestyle diseases such as diabetes and obesity.

In an early publication, we could show that striae distensae always develop perpendicular to the skin tension lines. In another article, we demonstrated that virtual skin tension lines are identical to the obvious Main Folding Lines; we recommended their use as optimal directions for orthopedic incisions, when inconspicuous scar formation is a prerequisite, as in children, younger adults, and women.

Using robots in surgeries dates back to the mid-1980s. The robotic was applied in a wide range of biological and medical sciences such as clinical medicine, neuroscience, cardiovascular, dentofacial, and cellular and molecular life sciences. Orthopedic robots are much more widely used and complex in medical engineering sciences.