Volume 1 | Issue 1 | DOI: https://doi.org/10.33696/Signaling.1.004
Activation of NLRP3 Inflammosome by N4-Acetyl Cytidine and Its Consequences
- 1Department of Neurology, the Third Affiliated Hospital of Guizhou Medical University, China
- 2Department of Neurology, Affiliated Hospital of Guizhou Medical University, China
- 3Medical Experimental Center of the Third Affiliated Hospital of Guizhou Medical University, Duyun, Guizhou 558000, China
Hua Bai, email@example.com
Received Date: February 14, 2020
Accepted Date: April 06, 2020
Bai H. Activation of NLRP3 Inflammosome by N4-Acetyl Cytidine and Its Consequences. J Cell Signal 2020; 1(1):14-17.
Copyright: © 2020 Bai H. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
It is now well accepted that the ionizing radiation-generated reactive oxygen species (ROS), that constitute ~2/3 of the effects of external beam radiation, do not only produce direct tumor cell death, but also affect the surrounding microenvironment. Moreover, this indirect effect of radiation may result in systemic effects, specifically the initiation of an inflammatory response.
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