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Journal of Cellular Signaling
ISSN: 2692-0638
Latest Articles
Potential Mechanism of CDC42 Promoting HCC Metastasis
Miaoling Tang , Rongni Feng , Jun Li
Hepatocellular carcinoma (HCC) is an aggressive malignancy with increasing morbidity and mortality worldwide. The migration and motility of HCC tumor cells are enhanced by the formation of invadopodia, which comprise membrane protrusions at the leading edge. Previous studies have showed that cell division cycle 42 (CDC42) plays an essential role in remodeling the cytoskeleton, which is associated with invadopodia formation and thus mediates cellular movement.
J Cell Signal, 2023, Volume 4, Issue 2, p49-55 | DOI: 10.33696/Signaling.4.091
Novel Drug Development for Treatment of COVID-19 by In Silico Analysis: Identification of SARS-Cov-2 Inhibiting Streptomyces Compounds
Jayant Kumar , Prachiti Gholap , Thulasi G Pillai
In accordance with the present epidemiological paradigm, viral mutations of the virus are on the rise, and their natural effects are being selected for at a higher rate than normal. According to the World Health Organization (WHO), the global COVID-19 pandemic induced by the Delta and Omicron strain of the SARS-CoV-2 virus could propagate and disseminate more rapidly than other viruses thanks to its many mutations, and these also caused some very significant health problems.
J Cell Signal, 2023, Volume 4, Issue 2, p56-72 | DOI: 10.33696/Signaling.4.092
A Study on the Usage of Probiotics as a Safer Antipyretic
Shantanu Shrivastava , Nimisha Bhatu
Most medicines and supplements which include probiotics have both expected clinical outcomes and unwanted side effects, which plays a major role when considering them as a mode of treatment. This review is an update about the advantages and disadvantages associated with the use of probiotics as part of a safe therapeutic armamentarium in health and other diseases. The advantages of probiotics run across multiple tissue systems in the body and a has a wide age spectrum.
J Cell Signal, 2023, Volume 4, Issue 2, p73-77 | DOI: 10.33696/Signaling.4.093
Understanding Chromosome Replication and Segregation Unit of Mycobacterium and Its Comparative Analysis with Model Organisms: From Drug Targets to Drug Identification
Preeti Jain
Bacterium maintains its pathogenicity in the host by continuing replication and adopting temporal and spatial coordination of cell division steps such as cell wall synthesis, DNA replication, chromosome segregation, Z ring assembly, septum formation and finally cytokinesis. This multistep process requires spatiotemporal assembly of macromolecular complexes and is probably regulated by redundant and multifunctional activities of cell replication and division proteins.
J Cell Signal, 2023, Volume 4, Issue 2, p78-85 | DOI: 10.33696/Signaling.4.094
