Journal of Cellular Signaling

Specific aims of the issue:

To publish original research, review articles and commentaries on the below topics:

• Role of oxidative stress in diabetes (T1D, T2D, maternal diabetes), obesity, cancer, etc.. It may include studies on specific cellular signaling pathways, treatment approaches, and phytochemicals used to reduce oxidative stress's effect during metabolic disorders.
• Oxidative stress and mitochondrial bioenergetics
• Endoplasmic Reticulum (ER) stress in the progression of diseases
• Advanced glycated end products in metabolic diseases
• Effect of oxidative stress on post-translational modifications regulating cellular signaling
• Membrane protein/transporter protein regulation during metabolic disorders
• Plant products/bioactive compounds regulating the oxido-reductive imbalance

Submission Guideline

Authors are advised to submit manuscripts directly to following editorial manager desk- https://jcs.manuscriptmanager.net/ or the author may directly send the manuscript along with all the necessary supplement documents to the following email address: signaling@scientific-archives.net

During submission, the author must assure that –

• Submissions must neither have been submitted nor published elsewhere.
• All the manuscripts submitted to this special issue will be peer-reviewed by two independent reviewers and selected in accordance with the journal standards.
• If choosing to contribute a review, please submit a brief (1-2 sentence description) for pre-review by the guest editors.

Oxidative Stress and Metabolic Disorders

Oxido-reductive imbalance causes cellular stress in terms of macromolecular damage leading to altered molecular signaling which ultimately becomes an essential factor in the development of a disease. Failure of the cellular antioxidative system and excessive ROS generation not only damages proteins and lipids but also modulates energy metabolism, cell cycle control, genetic mutations, inflammation, and cellular transport mechanisms. Several metabolic stress like high glucose, high fat diet, alcohol consumption, etc. may cause high oxidative stress. On the contrary, recent research has established a strong connection between oxidative stress and metabolic disorders like diabetes, obesity, and cancer. Studying the role of Oxidative stress in the etiology of metabolic disorders will not only help in understanding the pathophysiology of the disease but also enable the identification of novel therapeutic avenues for treatment.