Case Report Open Access
Volume 3 | Issue 1 | DOI: https://doi.org/10.33696/haematology.3.042

Phlebotomy in Congenital Erythrocytosis and in Sickle Cell Disease HbSC

  • 2Internal Medicine Department, Santa Maria degli Angeli Hospital, ASFO, Pordenone (PN), Italy
  • 1Blood Transfusion Department, Santa Maria degli Angeli Hospital, ASFO, Pordenone (PN), Italy
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Corresponding Author

Epifania Rita Testa, epifania.testa@asfo.sanita.fvg.it

Received Date: February 18, 2022

Accepted Date: March 03, 2022


The inherited haemoglobin disorders and the clinical laboratory is essential in the diagnosis. Phlebotomy is the therapeutic procedure indicated to reduce blood viscosity and decreasing the risk of thrombotic events in the haemoglobin variants with high affinity for O2 or vaso-occlusive crises in SCD with double heterozygosity HbSC. We describe how therapeutic bleeding remains the treatment in two variant haemoglobinopathies, Hb Regina and the Hb Trollhattanreported for the first time in the Italian population and a double heterozygosity HbSC. In patients with high haematocrit level when other secondary conditions of polyglobulia are excluded, a high liquid chromatography (HPLC) analysis for haemoglobin study should be suggested.


Haemoglobinopathy, Sickle cell disease, High liquid chromatography analysis, Polyglobulia, Phlebotomy

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