Commentary Open Access
Volume 4 | Issue 1 | DOI: https://doi.org/10.33696/Neurol.4.067
Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease
Peter G. Noakes1,2,*, William D. Phillips1, Rosalind L. Jeffree6, Frederik J. Steyn1,4,5, Ernst J. Wolvetang3, Rob D. Henderson4,5, Pamela A. McCombe4,5, Shyuan T. Ngo2,3,4,5
- 1School of Biomedical Sciences, The University of Queensland, St. Lucia QLD 4072 Australia
- 2Queensland Brain Institute, The University of Queensland, St. Lucia QLD 4072 Australia
- 3Australian Institute for Bioengineering and Nanotechnology, The University of Queensland, St. Lucia QLD 4072 Australia
- 4Department of Neurology, Royal Brisbane and Women’s Hospital, Herston QLD 4006, Australia
- 5University of Queensland Centre for Clinical Research, The University of Queensland Herston QLD 4006, Australia
- 6Department of Neurosurgery, Royal Brisbane and Women’s Hospital, Herston QLD 4006, Australia
Corresponding Author
Peter G. Noakes, p.noakes@uq.edu.au
Received Date: December 12, 2022
Accepted Date: January 02, 2023
Noakes PG, Phillips WD, Jeffree RL, Steyn FJ, Wolvetang EJ, Henderson RD, et al. Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease. J Exp Neurol. 2023;4(1):1-5.
Copyright: © 2023 Noakes PG, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Recommended Articles
Muscle and Its Neuromuscular Synapse – Players in the Pathogenesis of Motor Neuron Disease
Motor Neuron Disease (MND) of which Amyotrophic lateral sclerosis (ALS) is the most common form, is a devastating disorder where approximately 80% of patients die within 3-5 years of diagnosis. The highly variable clinical presentation, course, and prognosis between individuals suggests that a variety of factors underlie the pathogenesis of the disease.