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Journal of Cellular Immunology

ISSN: 2689-2812

Review Article Open Access
Volume 2 | Issue 2 | DOI: https://doi.org/10.33696/immunology.1.020

Multiple Roles of the Interleukin IL-17 Members in Breast Cancer and Beyond

Stephane Potteaux1,2,*, Jacqueline Lehmann-Che1, Armand Bensussan1, Richard Le Naour2, Yacine Merrouche2,3
  • 1Unité Inserm U976 (Immunologie humaine, Pathopysiologie, Immunothérapie); Hôpital Saint-Louis, 1 rue Claude Vellefaux, 75010 Paris, France
  • 2IRMAIC, EA7509, Université Reims-Champagne-Ardenne, 51 rue Cognacq-Jay, 51095 Reims CEDEX, France
  • 3Institut Godinot, 1 rue du Général Koenig, 51100 Reims, France
+ Affiliations - Affiliations

Corresponding Author

Stephane Potteaux, stephane.potteaux@inserm.fr

Received Date: January 22, 2020

Accepted Date: February 21, 2020

Citation:

Potteaux S, Lehmann-Che J, Bensussan A, Le Naour R, Merrouche Y. Multiple Roles of the Interleukin IL-17 Members in Breast Cancer and Beyond. J Cell Immunol. 2020; 2(2): 55-64.


Copyright: © 2020 Potteaux S, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Abstract

Interleukin-17 (IL-17) family proteins are involved in the control of infections. When unrestrained, these cytokines contribute to the development of chronic inflammatory diseases. The IL-17 family contains 6 members: IL-17A to F. In this review, we outline the current knowledge on the roles of each IL-17 member on breast cancer.

Keywords

IL-17, Breast tumor, Microenvironment, Cytokines, Stroma, Immune cells, Inflammation

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