Review Article Open Access
Volume 3 | Issue 2 | DOI: https://doi.org/10.33696/Signaling.3.071

Low-level Laser Therapy in the Oral Cavity: A Retrospection in the Future

  • 1DDS, MS Molecular Physiology, National Kapodistrian University of Athens, Greece
  • 2Biologist, PhD, University of Ancona Italy, Post-doctoral researcher, National Kapodistrian University of Athens, Greece
  • 3Associate Professor, Department of Periodontology, School of Dentistry, National Kapodistrian University of Athens, Greece
+ Affiliations - Affiliations

Corresponding Author

Ioannis K Karoussis, ikaroussis@dent.uoa.gr

Received Date: March 30, 2022

Accepted Date: April 28, 2022


Lasers have gained rather broad application in the field of medicine, as well as in dentistry. Different wave lengths are appropriate for a variety of uses, such as hemostasis, antimicrobial effect, tissue section and excision. Low level laser therapy (LLLT) is particularly interesting, since it stands out for its biostimulatory effect on tissues.

The aim of the present review is the presentation of the broad spectrum of use of LLLT in the oral cavity, of the current literature on the matter and the dynamic lasers exhibit affecting different cell populations.

Without it having been completely clear, there is a mechanism that leads to analgesia after LLLT application. In the field of dentistry, LLLT is extremely useful for complementary use on the non-surgical treatment of periodontitis and peri-implant diseases, with very promising results. Experimentally, it seems to have a tremendously positive effect on the proliferation and differentiation of various cellular lines.

That event has a double benefit, both on the acceleration of wound healing and on the faster and better osseointegration of titanium implants. Although the use of lasers has yet to be broadly accepted for all potential applications, there is great field for further research that will lead to more reliable and long-term results. The great heterogeneity of settings, which are applied, implies the need for more studies, so that specific protocols can finally be announced. However, lasers certainly help with patient relief, which is after all a dentist’s main target. Undoubtedly, their correct use depends on the clinician’s deep theoretical knowledge and clinical skill, so that unfortunate events are avoided.


Low Level Laser Therapy, LLLT, Human gingival fibroblasts, Soft laser therapy, Photobiomodulation, Wound healing, Inflammation

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