Short Communication Open Access
Volume 2 | Issue 1 | DOI: https://doi.org/10.33696/diabetes.1.012

Investigation of Regimen Adjustment for T2DM Patients Inadequately Controlled on Basal Insulin – Interpretation of the 4200 Study

  • 1Endocrinology and Metabolism Center of China-Japan Friendship Hospital, China
+ Affiliations - Affiliations

Corresponding Author

Wenying Yang, ywying_1010@163.com

Received Date: January 19, 2020

Accepted Date: March 17, 2020


The 4200 study is a randomized controlled trial, aimed to confirm the efficacy and safety of BIAsp 30 BID or TID in T2DM patients inadequately controlled on basal insulin, with 69% of the subjects recruited from mainland China. After 24 weeks of treatment, HbA1c level decreased comparably and hypoglycemia rates were similar between BIAsp BID and BIAsp TID groups. This study provided new evidence and inspiration for drug options in regimen adjustment for Chinese T2DM patients inadequately controlled on basal insulin.


T2DM, BIAsp 30, Insulin regimen switch

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