Mini Review Open Access
Volume 2 | Issue 4 | DOI: https://doi.org/10.33696/cardiology.2.021

Left Atrial Dysfunction in Patients with Coronary Slow Flow

  • 1Department of Cardiology, Affiliated Zhongshan Hospital of Dalian University, Dalian, Liaoning Province, China
  • 2Department of Cardiology, The Second Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, Shaanxi Province, China
  • 3Department of Cardiology, The Sanmenxia Central Hospital, Sanmenxia, Henan Province, China
+ Affiliations - Affiliations

Corresponding Author

Li Liu, lbeilliun@yahoo.com

Received Date: June 20, 2021

Accepted Date: September 17, 2021


The coronary slow flow phenomenon (CSFP) is relatively common in patients scheduled for coronary angiography, characterized by delayed distal vessel opacification of contrast in the absence of significant epicardial coronary stenosis. Rather than a simple angiographic curiosity, CSFP has significant clinical implications. Currently, its pathophysiological mechanism remains unclear although several possible mechanisms have been proposed. There is objective evidence of left ventricular systolic/diastolic dysfunction in patients with CSFP, however the alteration of left atrium (LA) function is controversial. LA serves an integral role in cardiac performance and is closely related to left ventricle function. In this review we will address the changes of LA structure and function in patients with CSFP according to our research and existing literature, therefore provide further insight into its clinical significance and pathophysiological mechanisms.


Coronary slow flow phenomenon, Left atrium structure and Function, Two-dimensional speckle tracking echocardiography, Strain, Strain rate

Author Information X