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Articles published in this issue are Open Access and licensed under Creative Commons Attribution License (CC BY NC) where the readers can reuse, download, distribute the article in whole or part by mentioning proper credits to the authors.
Macrophage Activation Syndrome: An Atypical Initial Presentation of Systemic Lupus Erythematosus
Macrophage Activation Syndrome (MAS) is a severe inflammatory complication often linked to autoimmune disorders such as systemic lupus erythematosus (SLE). We describe a 57-year-old woman who presented with persistent fever, polyarthralgia, pancytopenia, and markedly elevated ferritin levels (>40,000 ng/mL). Extensive evaluation ruled out infection and malignancy. A diagnosis of MAS was made, and she responded well to high-dose corticosteroids and anakinra.