Journal of AIDS and HIV Treatment

Commentary Open Access

Commentary – HIV-Induced Extracranial Carotid Ectasia and Stroke

Rakhee Lalla, Prashant Raghavan, John W. Cole

HIV is a known risk factor for both ischemic and hemorrhagic stroke. Even with the widespread use of antiretroviral therapy, stroke incidence is higher in patients with HIV compared to non-HIV control subjects.

Research Article Open Access

Older Versus Younger Men Who Have Sex with Men: Awareness of and Potential Barriers to the Use of Pre-Exposure Prophylaxis (PrEP) Medication to Prevent the Transmission of HIV

Hugh Klein, Thomas Alex Washington

Men who have sex with other men (MSM) comprise the single largest group of individuals contracting HIV in the United States, accounting for more than one-half of all new HIV diagnoses.

Review Article Open Access

Use of Humanized Mouse Models for Studying HIV-1 Infection, Pathogenesis and Persistence

Matthew Weichseldorfer, Alonso Heredia, Marvin Reitz, Joseph L. Bryant

Different humanized mouse models have been introduced to enable HIV-1 research in vivo, which has been made possible by the development of immunodeficient mouse strains.

Research Article Open Access

Development of an Ultrasensitive HIV-1 DNA Detection Assay Based on an Automated πCode End-Point PCR System

Kazuo Suzuki, Jui-Yu Hu, Takaomi Ishida, Yuhung Lin, Satoshi Minote, Zhixin Liu, Julie Yeung, Leon Patrick McNally, Mitchell Starr, Angelique Levert, Philip Cunningham, John Zaunders, Chin-Shiou Huang

Currently, around 60-75% of the HIV positive patients in developed countries on anti-retroviral therapy (ART) have undetectable plasma viral load using current diagnostic PCR assays.

Research Article Open Access

HIV-1 Treatment Failure among Population Taking Antiretroviral Therapy in Ethiopia

Atsbeha G Egziabhier, Kidist Zealiyas, Rahel Tilahun, Mulu Girma, Gebremedihin G/Michael, Tekalign Deressa, Ebba Abate, Desta Kassa, Yibeltal Assefa

For more than 35 years, the world has grappled with an AIDS epidemic that has claimed an estimated 35.0 million [28.9 million-41.5 million] lives and at its peak threatened global stability and security.

Research Article Open Access

Assessment of Attitudes toward HIV and AIDS among Undergraduate Students at a Historically Black University

Prince Andrew, Azad R. Bhuiyan, Anthony Mawson, Mohammad Shahbazi

HIV is no longer only a public health challenge, but also a global threat with a devastating negative impact that has claimed over 35 million lives globally. In 2017, about 36.9 million people live with HIV, and 1.8 million people becoming newly infected with the disease globally [1].

Mini Review Open Access

CCR5 Inhibitors and HIV-1 Infection

Olga S. Latinovic, Marvin Reitz, Alonso Heredia

Cellular components are attractive targets for antiviral therapy because they do not mutate as readily as do viral proteins do [1-3]. The identification of CCR₅ as an HIV-1 coreceptor [4-7], facilitated by the discovery of the antiviral activities of CCR₅ ligand ?-chemokines [8], resulted in the development of new viral entry inhibitors to block CCR₅ binding, including both- small molecules and CCR₅ antibodies