Journal of AIDS and HIV Treatment

Review Article Open Access

Potential Advantages of a Well-balanced Nutrition Regimen for People Living with Human Immunodeficiency Virus Type -1

Daniele Basta, Olga S. Latinovic, Yutaka Tagaya, Giovannino Silvestri

This review underscores the important role of nutrition in enhancing the management of Human Immunodeficiency Virus type 1 (HIV-1). Highlighting the efficacy of dietary interventions, including, the importance of omega-3 fatty acids, vitamins D and B-12, and the Mediterranean diet, we delineate how these beneficial nutritional strategies can improve the effectiveness of combined antiretroviral therapy (cART), mitigate its side effects, and ameliorate metabolic disorders in people living with HIV-1 (PLWH). 

Research Article Open Access

Patient Satisfaction and Perceptions Regarding Anti-Retroviral Therapy (ART) Services in Rural Southwestern Uganda

Amunyongire R, Nuwagaba E, Atuhaire J, Nduhuura E, Ndebiika A, Turyasingura O, Ntaro M, Rukundo GZ, Grace Nambozi

Patient satisfaction and perception of the healthcare services received contribute to compliance with treatment guidelines, retention in care, and adherence to recommendations. This is especially so in the treatment of chronic medical conditions such as HIV/AIDS. The success of antiretroviral therapy (ART) plays a fundamental role in determining the quality of life of people living with HIV/AIDS (PLWHAs).

Mini Review Open Access

Known and New Routes to Neutralize HIV-1 with Camelid Single Chain Antibody Fragments

C. Theo Verrips, Gerben ten Hag, Ursula Dietrich, Harold Marcotte

In spite of all efforts to reduce transmission of HIV-1, 1.7 million persons were infected in 2019 worldwide. Whereas in the developed countries the COVID-19 pandemic is reasonably controlled within 2 years because of the fast and successful development of vaccines, nearly 40 years after the first reported cases of AIDS due to HIV-1 and in spite of tremendous efforts to develop vaccines against HIV-1, there are still no vaccines against the virus.

Research Article Open Access

Pregnancy Outcomes in Pregnant Women with HIV on Tenofovir Disoproxil Fumarate (TDF) Compared to Tenofovir Alafenamide (TAF)

Matthew A. Thimm, Alison Livingston, Rosemary Ramroop, Ahizechukwu C. Eke

HIV infection in pregnancy continues to be of significant clinical and public health importance [1,2]. The current statistics published by the World Health Organization (WHO) demonstrate that 38 million people are living with HIV in 2019, and 1.1 million (85%) pregnant women living with HIV received antiretroviral therapy (ARVs) during pregnancy and postpartum.

Commentary Open Access

Fostemsavir in Heavily Treatment-Experienced Individuals Living with HIV-1: Insights from the Phase 3 BRIGHTE Study

Max Lataillade, Peter Ackerman, Till Schoofs, Andrew Clark, Michael Kozal

Fostemsavir (Rukobia^™, ViiV Healthcare, Research Triangle Park, NC), a prodrug of the first-in-class attachment inhibitor temsavir, was developed to provide a much-needed new therapeutic option for heavily treatment-experienced (HTE) people living with HIV-1 (PLWH) who are unable to form a suppressive regimen from remaining viable antiretroviral (ARV) agents because of multidrug resistance, contraindications, prior intolerance, or other safety considerations.

Mini Review Open Access

Pre-Exposure Prophylaxis (PrEP) Safety and Tolerability in Individuals ≥ 45 Years Old

Emily Comstock, Camilia James, Robert Hegarty, Yolanda Flores, Anthony Amoroso, Rohit Talwani, Eleanor Wilson

Pre-exposure prophylaxis (PrEP) is a combination of antiretroviral medications, most commonly prescribed as two co-formulated antiretrovirals, taken as a single tablet daily to significantly reduce the risk of human immunodeficiency virus (HIV) infection in individuals at high risk.

Review Article Open Access

Black Women's Contribution to the HIV/AIDS Fight

Raphael M. Mutepa, Samson Chama

After thousands of years of gender conflicts, the world now stands at the beginning of the feminine era, when women will rise to their proper standing, and the entire world will experience the harmony between men and women.

Research Article Open Access

Development of an Ultrasensitive HIV-1 DNA Detection Assay Based on an Automated πCode End-Point PCR System

Kazuo Suzuki, Jui-Yu Hu, Takaomi Ishida, Yuhung Lin, Satoshi Minote, Zhixin Liu, Julie Yeung, Leon Patrick McNally, Mitchell Starr, Angelique Levert, Philip Cunningham, John Zaunders, Chin-Shiou Huang

Currently, around 60-75% of the HIV positive patients in developed countries on anti-retroviral therapy (ART) have undetectable plasma viral load using current diagnostic PCR assays.

Research Article Open Access

Health Workers’ Perspectives on the Outcomes, Enablers, and Barriers to the Implementation of HIV “Test and Treat” Guidelines in Abuja, Nigeria

Solomon Odafe, Kristen A. Stafford, Aliyu Gambo, Dennis Onotu, Mahesh Swaminathan, Ibrahim Dalhatu, Uzoma Ene, Oladipo Ademola, Ahmed Mukhtar, Ibrahim Ramat, Ehoche Akipu, Henry Debem, Andrew T. Boyd, Aboje Sunday, Bola Gobir, Man E. Charurat

HIV/AIDS continues to be a major public health disease accounting for 35 million deaths across the world. In 2016 alone, there were 1.8 million new HIV infections and 1 million deaths worldwide.

Case Report Open Access

Primary Lymph Node Kaposi's Sarcoma in Two HIV Positive Patients Presenting with Generalized Lymphadenopathy and Pancytopenia in a Third Level Hospital in Guatemala

Pablo Pérez Pinetta, Johanna Meléndez

We present two unique cases in which two HIV positive patients with generalized lymphadenopathy and pancytopenia without any skin lesions were diagnosed with primary lymph node Kaposi´s Sarcoma after excisional biopsy of an inguinal lymph node.