Archives of Obstetrics and Gynaecology

Review Article Open Access

Bacterial Profile and Drug Resistance Patterns among Pregnant Women with Bacteriuria in East Africa: A Systematic Review and Meta Analysis

Molla Getie Mehari , Mekdes Molla

Due mostly to the growth of multidrug resistant infections, antimicrobial resistance (AMR) has limited the arsenal of medical professionals against infectious diseases on a global scale. Thus, the purpose of this systematic review and meta-analysis is to present the pooled prevalence, bacterial profile, and current trend of antibiotic resistance in pregnant women who have significant bacteriuria in East Africa.

Review Article Open Access

The Effectiveness of Methotrexate in Hemodynamically Stable Women with Tubal Ectopic Pregnancy: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Hossam Abdelfatah Mansour , Ruqayyah Ali Ahmed , Ahmed Mohamed , Ekramy A. Mohamed

Background: Ectopic pregnancy (EP) is a leading cause of acute abdominal pain in gynecology. Most women with tubal EP present hemodynamically stable, making non-surgical therapy a viable option. This study aimed to evaluate the effectiveness and safety of methotrexate (MTX) regimens in this population. Methods: We performed a systematic review and meta-analysis of randomized controlled trials (RCTs). A comprehensive search of PubMed, Cochrane Library, Embase, LILACS, SciELO, and CINAHL was conducted from database inception to April 2025.

Editorial Open Access

Comprehensive Management of Endometriosis: Implementation from Research to Clinical Practice

Elliot M. Levine , Carlos M. Fernandez , Teresa Tam

Appendiceal endometriosis (AE) represents a clinically significant yet frequently overlooked manifestation of endometriosis that may contribute to persistent symptoms and suboptimal treatment outcomes. Multiple comprehensive reviews demonstrate that appendiceal involvement occurs in a notable percentage of women with endometriosis and can present with distinctive symptom patterns.

Review Article Open Access

Research Progress of Molecular Classification Guiding Targeted Therapy Combined with Fertility-Preserving Treatment for Endometrial Cancer

Xiyao Ma , Yuanjing Hu

In recent years, the incidence of endometrial cancer has continued to increase and tends to be younger. An increasing number of young patients wish to preserve reproductive function during treatment. Although progestin therapy has a high remission rate, some patients experience hormone resistance, recurrence, or even disease progression, making this traditional treatment unsuitable for everyone.

Commentary Open Access

Shared Experiences and Reflections on Sexual and Reproductive Health Rights

Maheshor Kaphle , Nirmala Regmi

Male involvement in sexual and reproductive health (SRH) is increasingly recognized as a crucial factor for improving maternal, neonatal, and family well-being. This paper shares personal, peer, and community experiences from Nepal, highlighting both the benefits and barriers to men’s engagement in SRH.